STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmMConserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa)    
Predicted Functional Partners:
ECA1016
Putative membrane protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ygdd ygdd or b2807 or c3377 or z4124 or ecs3667 or sf2821 SWALL:AAN44308 (EMBL:X73413) (131 aa) fasta scores: E(): 1.9e-42, 78.62% id in 131 aa, and to Salmonella typhimurium, and Salmonella typhi putative small membrane protein ygdd or stm2981 or sty3121 SWALL:Q8XEU8 (EMBL:AE008836) (131 aa) fasta scores: E(): 3.7e-41, 75.57% id in 131 aa.
  
  
 0.901
ECA2747
Similar to Escherichia coli 37 kDa nucleoid-associated protein yejk or b2186 SWALL:NA37_ECOLI (SWALL:P33920) (334 aa) fasta scores: E(): 2.6e-104, 80.53% id in 334 aa.
  
    0.583
gcvA
Glycine cleavage system transcriptional activator; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glycine cleavage system transcriptional activator GcvA or b2808 or c3378 or z4125 or ecs3668 SWALL:GCVA_ECOLI (SWALL:P32064) (305 aa) fasta scores: E(): 1.1e-112, 91.44% id in 304 aa, and to Shigella flexneri positive regulator of gcv operon GcvA or sf2822 SWALL:AAN44309 (EMBL:AE015295) (305 aa) fasta scores: E(): 1.5e-112, 91.44% id in 304 aa; Belongs to the LysR transcriptional regulatory family.
  
    0.582
ECA3711
Conserved hypothetical phage-related protein; Similar to many proteins described as nucleoid-associated proteins e.g. Escherichia coli nucleoid-associated protein NdpA or b2186 SWALL:NDPA_ECOLI (SWALL:P33920) (334 aa) fasta scores: E(): 1.7e-18, 28.22% id in 333 aa. Also similar to many others e.g. Ralstonia oxalatica hypothetical protein SWALL:CAD61113 (EMBL:AJ536756) (340 aa) fasta scores: E(): 8.2e-41, 38.34% id in 326 aa; Similar to, and to Pseudomonas resinovorans hypothetical protein or93 SWALL:BAC41613 (EMBL:AB088420) (333 aa) fasta scores: E(): 1.9e-30, 30.12% id in 332 aa.
  
    0.508
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.499
ECA1019
Lysine decarboxylase family protein; Similar to Salmonella typhimurium putative nucleotide binding ygdh or stm2969 SWALL:Q8ZMD2 (EMBL:AE008836) (454 aa) fasta scores: E(): 4.8e-158, 86.78% id in 454 aa, and to Yersinia pestis hypothetical protein ypo1033 or y3148 SWALL:AAM86698 (EMBL:AJ414146) (454 aa) fasta scores: E(): 2e-157, 86.12% id in 454 aa.
  
     0.479
pepQ
Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position.
  
     0.475
recX
Regulatory protein Recx; Modulates RecA activity; Belongs to the RecX family.
  
   
 0.456
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.442
ECA1856
Putative FAD-binding oxidase; Similar to Yersinia pestis hypothetical protein ypo2407 or y1932 SWALL:AAM85498 (EMBL:AJ414152) (1018 aa) fasta scores: E(): 0, 82.41% id in 1018 aa, and to Escherichia coli hypothetical protein ydij or b1687 SWALL:YDIJ_ECOLI (SWALL:P77748) (1018 aa) fasta scores: E(): 0, 79.05% id in 1017 aa.
  
     0.434
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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