STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA1025Putative RNA pseudouridylate synthase; Similar to Yersinia pestis hypothetical protein ypo1038 or y3143 SWALL:Q8ZH72 (EMBL:AJ414146) (257 aa) fasta scores: E(): 3.4e-82, 75.39% id in 256 aa, and to Escherichia coli O157:H7 hypothetical protein z4107 or ecs3651 SWALL:Q8X6T6 (EMBL:AE005507) (260 aa) fasta scores: E(): 1.4e-75, 71.37% id in 255 aa. (261 aa)    
Predicted Functional Partners:
ECA1024
Similar to Yersinia pestis hypothetical protein Ypo1037 SWALL:Q8ZH73 (EMBL:AJ414146) (110 aa) fasta scores: E(): 9.2e-20, 55.04% id in 109 aa, and to Salmonella typhi hypothetical protein yqcc or sty3104 SWALL:Q8Z438 (EMBL:AL627276) (109 aa) fasta scores: E(): 3.6e-15, 45.79% id in 107 aa.
  
  
 0.887
ECA1026
Putative flavodoxin; Similar to Yersinia pestis hypothetical protein ypo1039 or y3142 SWALL:Q8ZH71 (EMBL:AJ414146) (149 aa) fasta scores: E(): 1.2e-39, 68.91% id in 148 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yqca or b2790 or z4106 or ecs3650 or sf2803 SWALL:AAN44291 (EMBL:U29581) (149 aa) fasta scores: E(): 9.2e-37, 66.89% id in 148 aa.
  
    0.681
ECA1023
Similar to Neisseria meningitidis transcriptional regulator, MarR family nmb1585 SWALL:Q9JYH5 (EMBL:AE002509) (143 aa) fasta scores: E(): 1.1e-18, 40.71% id in 140 aa, and to Neisseria meningitidis putative transcriptional regulator nma1774 SWALL:Q9JTH6 (EMBL:AL162757) (120 aa) fasta scores: E(): 2.4e-15, 45.53% id in 112 aa.
 
     0.619
rplC
50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
 
 0.548
rplQ
50S ribosomal protein L17; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 50S ribosomal protein L17 RplQ or b3294 or c4055 or z4664 or ecs4159 or sf3326 SWALL:RL17_ECOLI (SWALL:P02416) (127 aa) fasta scores: E(): 1.2e-44, 99.16% id in 119 aa.
 
   0.536
rplM
50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 
 0.505
obg
Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
 
 0.505
truD
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
    
 
 0.500
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.473
rplO
50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
   0.463
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.