STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1027Similar to Yersinia pestis hypothetical protein ypo1040 or y3141 SWALL:AAM86691 (EMBL:AJ414146) (129 aa) fasta scores: E(): 3.2e-38, 84.49% id in 129 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yaeh or b0163 or c0200 or z0175 or ecs0167 or sf0155 SWALL:AAN41817 (EMBL:D26562) (128 aa) fasta scores: E(): 8.4e-38, 85.82% id in 127 aa; Belongs to the UPF0325 family. (129 aa)    
Predicted Functional Partners:
ECA3599
Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical protein ytfk or b4217 or c5315 SWALL:YTFK_ECOLI (SWALL:P39318) (68 aa) fasta scores: E(): 2.1e-19, 79.1% id in 67 aa, and to Yersinia pestis hypothetical protein ypo3527 or y0656 SWALL:AAM84244 (EMBL:AJ414157) (70 aa) fasta scores: E(): 6.1e-19, 77.27% id in 66 aa.
  
  
 0.718
crl
Curlin genes transcriptional activator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.
  
     0.709
wzyE
Putative ECA polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.
  
     0.675
lpp
Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
  
     0.660
ECA1145
Similar to Yersinia pestis putative lipoprotein ypo3161 or y1024 SWALL:AAM84605 (EMBL:AJ414155) (192 aa) fasta scores: E(): 7.8e-54, 80.2% id in 192 aa, and to Salmonella typhi putative lipoprotein sty0487 SWALL:Q8Z8V2 (EMBL:AL627266) (192 aa) fasta scores: E(): 2.3e-47, 68.75% id in 192 aa.
  
     0.658
ECA2287
Conserved hypothetical protein; Similar to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein SWALL:AAO69255 (EMBL:AE016839) (83 aa) fasta scores: E(): 3.7e-19, 66.26% id in 83 aa, and to Yersinia pestis hypothetical protein ypo2217 ypo2217 or y2058 SWALL:Q8ZEF6 (EMBL:AJ414151) (83 aa) fasta scores: E(): 5e-19, 71.42% id in 77 aa.
  
     0.639
viaA
Similar to Escherichia coli O6 hypothetical protein YieM SWALL:AAN83105 (EMBL:AE016769) (483 aa) fasta scores: E(): 1.1e-124, 63.03% id in 487 aa.
  
     0.630
glnD
[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
       0.622
dapD
Similar to Escherichia coli, and Shigella flexneri 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD or b0166 or sf0156 SWALL:DAPD_ECOLI (SWALL:P03948) (274 aa) fasta scores: E(): 4.7e-99, 91.94% id in 273 aa, and to Salmonella typhimurium 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase DapD or stm0213 SWALL:Q8ZRP4 (EMBL:AE008704) (274 aa) fasta scores: E(): 2e-98, 90.11% id in 273 aa; Belongs to the transferase hexapeptide repeat family.
       0.617
cyaA
Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family.
  
     0.607
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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