STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (253 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphatidate cytidylyltransferase cdsa or cds or b0175 or z0186 or ecs0177 or sf0165 SWALL:CDSA_ECOLI (SWALL:P06466) (249 aa) fasta scores: E(): 2.5e-74, 74.08% id in 247 aa; Belongs to the CDS family.
 
  
 0.979
ispB
Octaprenyl-diphosphate synthase; Similar to Escherichia coli, and Shigella flexneri octaprenyl-diphosphate synthase IspB or Cel or b3187 or sf3227 SWALL:ISPB_ECOLI (SWALL:P19641) (323 aa) fasta scores: E(): 7.9e-100, 83.54% id in 322 aa; Belongs to the FPP/GGPP synthase family.
 
 
 0.966
ispA
Geranyltranstransferase; Similar to Escherichia coli geranyltranstransferase IspA or b0421 SWALL:ISPA_ECOLI (SWALL:P22939) (299 aa) fasta scores: E(): 4.8e-79, 71.76% id in 301 aa; Belongs to the FPP/GGPP synthase family.
 
 
 0.964
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
  
  
 0.933
bacA
Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
     
 0.930
ecfE
Protease; Similar to Escherichia coli, and Escherichia coli O157:H7 protease EcfE or b0176 or z0187 or ecs0178 SWALL:ECFE_ECOLI (SWALL:P37764) (450 aa) fasta scores: E(): 3.8e-131, 73.83% id in 451 aa, and to Salmonella typhimurium protease EcfE or stm0223 SWALL:ECFE_SALTY (SWALL:Q8ZRP1) (450 aa) fasta scores: E(): 1.9e-138, 78.27% id in 451 aa.
  
  
 0.901
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
  
 0.825
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.776
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
  
 0.710
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
  
 0.686
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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