STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ecfEProtease; Similar to Escherichia coli, and Escherichia coli O157:H7 protease EcfE or b0176 or z0187 or ecs0178 SWALL:ECFE_ECOLI (SWALL:P37764) (450 aa) fasta scores: E(): 3.8e-131, 73.83% id in 451 aa, and to Salmonella typhimurium protease EcfE or stm0223 SWALL:ECFE_SALTY (SWALL:Q8ZRP1) (450 aa) fasta scores: E(): 1.9e-138, 78.27% id in 451 aa. (451 aa)    
Predicted Functional Partners:
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
 0.969
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
  
  
 0.901
cdsA
Phosphatidate cytidylyltransferase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphatidate cytidylyltransferase cdsa or cds or b0175 or z0186 or ecs0177 or sf0165 SWALL:CDSA_ECOLI (SWALL:P06466) (249 aa) fasta scores: E(): 2.5e-74, 74.08% id in 247 aa; Belongs to the CDS family.
  
    0.880
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
  
  
 0.727
ompH
Outer membrane protein; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
  
  
 0.718
ECA2483
Putative peptidase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical metalloprotease yeba precursor yeba or b1856 or c2270 or sf1866 SWALL:YEBA_ECOLI (SWALL:P24204) (440 aa) fasta scores: E(): 6.7e-128, 75.11% id in 442 aa, and to Salmonella typhimurium putative peptidase yeba or stm1890 SWALL:Q8ZNV9 (EMBL:AE008784) (439 aa) fasta scores: E(): 5.8e-128, 75.05% id in 441 aa.
 
  
 0.672
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
  
  
 0.624
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
  
    0.615
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
 
  
 0.603
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.579
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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