STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fabZ(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa)    
Predicted Functional Partners:
lpxA
acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 0.986
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or b1288 or z2512 or ecs1861 or sf1293 SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 1.6e-84, 86.97% id in 261 aa.
 
 
 0.966
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.960
fabA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 
 0.932
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
  
 0.928
ECA4492
Similar to Actinobacillus actinomycetemcomitans 3-oxoacyl-[acyl-carrier protein] reductase fabG SWALL:FABG_ACTAC (SWALL:P70720) (242 aa) fasta scores: E(): 1.5e-46, 56.19% id in 242 aa, and to Escherichia coli O6 3-oxoacyl-[acyl-carrier protein] reductase c1187 SWALL:Q8FJ14 (EMBL:AE016758) (243 aa) fasta scores: E(): 7.9e-68, 79.83% id in 243 aa.
 
 0.928
ECA1208
Probable short chain dehydrogenase; Similar to Rhizobium meliloti putative sdr family dehydrogenase protein rb0961 or smb21383 SWALL:Q92UX4 (EMBL:AL603645) (296 aa) fasta scores: E(): 7.1e-51, 57.04% id in 291 aa, and to Xanthomonas axonopodis short chain dehydrogenase xac0083 SWALL:Q8PR80 (EMBL:AE011631) (245 aa) fasta scores: E(): 1.4e-40, 55.83% id in 240 aa.
 
 0.927
lpxC
UDP-3-o-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
    
 0.921
ECA1209
Probable short chain dehydrogenase; Similar to Rhizobium meliloti putative sdr family dehydrogenase protein rb0961 or smb21383 SWALL:Q92UX4 (EMBL:AL603645) (296 aa) fasta scores: E(): 1e-56, 60.87% id in 299 aa, and to Xanthomonas axonopodis short chain dehydrogenase xac0083 SWALL:Q8PR80 (EMBL:AE011631) (245 aa) fasta scores: E(): 2.6e-45, 57.5% id in 240 aa.
  
 0.916
ECA3767
Similar to Pseudomonas aeruginosa probable short-chain dehydrogenase pa4162 SWALL:Q9HWL9 (EMBL:AE004832) (238 aa) fasta scores: E(): 8.7e-18, 39.58% id in 240 aa, and to Bradyrhizobium japonicum Blr3403 protein blr3403 SWALL:BAC48668 (EMBL:AP005947) (242 aa) fasta scores: E(): 4.5e-18, 35.19% id in 233 aa.
  
 0.916
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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