| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0593 | mutL | ECA0593 | ECA3936 | Similar to Vibrio cholerae DNA repair protein RadC homolog SWALL:RADC_VIBCH (SWALL:Q9KVC9) (224 aa) fasta scores: E(): 2.2e-28, 55.47% id in 137 aa, and to Escherichia coli DNA repair protein RadC SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 2.4e-26, 50.38% id in 129 aa; Belongs to the UPF0758 family. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.435 |
| ECA0593 | mutS | ECA0593 | ECA1053 | Similar to Vibrio cholerae DNA repair protein RadC homolog SWALL:RADC_VIBCH (SWALL:Q9KVC9) (224 aa) fasta scores: E(): 2.2e-28, 55.47% id in 137 aa, and to Escherichia coli DNA repair protein RadC SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 2.4e-26, 50.38% id in 129 aa; Belongs to the UPF0758 family. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.612 |
| ECA0649 | dnaN | ECA0649 | ECA4440 | Weakly similar to Schizosaccharomyces pombe putative DNA mismatch repair protein, mlh1 homolog spbc1703.04 SWALL:Q9P7W6 (EMBL:AL136536) (684 aa) fasta scores: E(): 0.11, 21.48% id in 498 aa, and to Neisseria meningitidis hypothetical protein Nma0428 nma0428 SWALL:Q9JWD7 (EMBL:AL162753) (548 aa) fasta scores: E(): 0.18, 22.37% id in 523 aa. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.826 |
| ECA0649 | mutS | ECA0649 | ECA1053 | Weakly similar to Schizosaccharomyces pombe putative DNA mismatch repair protein, mlh1 homolog spbc1703.04 SWALL:Q9P7W6 (EMBL:AL136536) (684 aa) fasta scores: E(): 0.11, 21.48% id in 498 aa, and to Neisseria meningitidis hypothetical protein Nma0428 nma0428 SWALL:Q9JWD7 (EMBL:AL162753) (548 aa) fasta scores: E(): 0.18, 22.37% id in 523 aa. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.964 |
| ECA0649 | polA | ECA0649 | ECA0021 | Weakly similar to Schizosaccharomyces pombe putative DNA mismatch repair protein, mlh1 homolog spbc1703.04 SWALL:Q9P7W6 (EMBL:AL136536) (684 aa) fasta scores: E(): 0.11, 21.48% id in 498 aa, and to Neisseria meningitidis hypothetical protein Nma0428 nma0428 SWALL:Q9JWD7 (EMBL:AL162753) (548 aa) fasta scores: E(): 0.18, 22.37% id in 523 aa. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.780 |
| ECA0649 | recQ | ECA0649 | ECA4172 | Weakly similar to Schizosaccharomyces pombe putative DNA mismatch repair protein, mlh1 homolog spbc1703.04 SWALL:Q9P7W6 (EMBL:AL136536) (684 aa) fasta scores: E(): 0.11, 21.48% id in 498 aa, and to Neisseria meningitidis hypothetical protein Nma0428 nma0428 SWALL:Q9JWD7 (EMBL:AL162753) (548 aa) fasta scores: E(): 0.18, 22.37% id in 523 aa. | Similar to Escherichia coli ATP-dependent DNA helicase RecQ or b3822 SWALL:RECQ_ECOLI (SWALL:P15043) (607 aa) fasta scores: E(): 1.4e-198, 80.66% id in 605 aa. | 0.707 |
| ECA0649 | xni | ECA0649 | ECA1018 | Weakly similar to Schizosaccharomyces pombe putative DNA mismatch repair protein, mlh1 homolog spbc1703.04 SWALL:Q9P7W6 (EMBL:AL136536) (684 aa) fasta scores: E(): 0.11, 21.48% id in 498 aa, and to Neisseria meningitidis hypothetical protein Nma0428 nma0428 SWALL:Q9JWD7 (EMBL:AL162753) (548 aa) fasta scores: E(): 0.18, 22.37% id in 523 aa. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.684 |
| ECA2855 | mutL | ECA2855 | ECA3936 | Conserved hypothetical protein; Similar to Shigella flexneri intergenic-region protein yees or sf2996 SWALL:AAN44477 (EMBL:AE015313) (163 aa) fasta scores: E(): 4.9e-27, 50.65% id in 152 aa, and to Escherichia coli intergenic-region protein SWALL:Q8VRA3 (EMBL:AF447814) (163 aa) fasta scores: E(): 5.7e-27, 50.65% id in 152 aa, and to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 5.6e-23, 47.51% id in 141 aa; Belongs to the UPF0758 family. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.433 |
| ECA2855 | mutS | ECA2855 | ECA1053 | Conserved hypothetical protein; Similar to Shigella flexneri intergenic-region protein yees or sf2996 SWALL:AAN44477 (EMBL:AE015313) (163 aa) fasta scores: E(): 4.9e-27, 50.65% id in 152 aa, and to Escherichia coli intergenic-region protein SWALL:Q8VRA3 (EMBL:AF447814) (163 aa) fasta scores: E(): 5.7e-27, 50.65% id in 152 aa, and to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 5.6e-23, 47.51% id in 141 aa; Belongs to the UPF0758 family. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.602 |
| dnaN | ECA0649 | ECA4440 | ECA0649 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Weakly similar to Schizosaccharomyces pombe putative DNA mismatch repair protein, mlh1 homolog spbc1703.04 SWALL:Q9P7W6 (EMBL:AL136536) (684 aa) fasta scores: E(): 0.11, 21.48% id in 498 aa, and to Neisseria meningitidis hypothetical protein Nma0428 nma0428 SWALL:Q9JWD7 (EMBL:AL162753) (548 aa) fasta scores: E(): 0.18, 22.37% id in 523 aa. | 0.826 |
| dnaN | mutL | ECA4440 | ECA3936 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.871 |
| dnaN | mutS | ECA4440 | ECA1053 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.955 |
| dnaN | polA | ECA4440 | ECA0021 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
| dnaN | recJ | ECA4440 | ECA0772 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Similar to Escherichia coli single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ECOLI (SWALL:P21893) (577 aa) fasta scores: E(): 3.5e-163, 71.03% id in 580 aa, and to Erwinia chrysanthemi single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ERWCH (SWALL:P39693) (575 aa) fasta scores: E(): 6.8e-178, 78.44% id in 580 aa. | 0.501 |
| dnaN | recQ | ECA4440 | ECA4172 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Similar to Escherichia coli ATP-dependent DNA helicase RecQ or b3822 SWALL:RECQ_ECOLI (SWALL:P15043) (607 aa) fasta scores: E(): 1.4e-198, 80.66% id in 605 aa. | 0.680 |
| dnaN | xni | ECA4440 | ECA1018 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.947 |
| mutL | ECA0593 | ECA3936 | ECA0593 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Similar to Vibrio cholerae DNA repair protein RadC homolog SWALL:RADC_VIBCH (SWALL:Q9KVC9) (224 aa) fasta scores: E(): 2.2e-28, 55.47% id in 137 aa, and to Escherichia coli DNA repair protein RadC SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 2.4e-26, 50.38% id in 129 aa; Belongs to the UPF0758 family. | 0.435 |
| mutL | ECA2855 | ECA3936 | ECA2855 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Conserved hypothetical protein; Similar to Shigella flexneri intergenic-region protein yees or sf2996 SWALL:AAN44477 (EMBL:AE015313) (163 aa) fasta scores: E(): 4.9e-27, 50.65% id in 152 aa, and to Escherichia coli intergenic-region protein SWALL:Q8VRA3 (EMBL:AF447814) (163 aa) fasta scores: E(): 5.7e-27, 50.65% id in 152 aa, and to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 5.6e-23, 47.51% id in 141 aa; Belongs to the UPF0758 family. | 0.433 |
| mutL | dnaN | ECA3936 | ECA4440 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.871 |
| mutL | mutS | ECA3936 | ECA1053 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.992 |