STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fecISimilar to Escherichia coli probable RNA polymerase sigma factor FecI or b4293 SWALL:FECI_ECOLI (SWALL:P23484) (173 aa) fasta scores: E(): 1.1e-48, 78.61% id in 173 aa, and to Shigella flexneri 2a FecI SWALL:AAL08458 (EMBL:AF326777) (173 aa) fasta scores: E(): 1.1e-48, 78.61% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. (173 aa)    
Predicted Functional Partners:
fecR
iron(III) dicitrate sensor protein; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 7.6e-87, 69.55% id in 312 aa, and to Shigella flexneri 2a FecR SWALL:AAL08457 (EMBL:AF326777) (317 aa) fasta scores: E(): 7.6e-87, 69.55% id in 312 aa.
 
 
 0.988
fecA
iron(III) dicitrate transport protein; Similar to Escherichia coli iron FecA or b4291 SWALL:FECA_ECOLI (SWALL:P13036) (774 aa) fasta scores: E(): 0, 80.56% id in 782 aa, and to Pseudomonas aeruginosa FecA or pa3901 SWALL:Q9HXB2 (EMBL:AE004807) (784 aa) fasta scores: E(): 1.6e-196, 62.43% id in 788 aa.
 
  
 0.942
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
  
 
 0.864
ECA1273
Putative sensor protein; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 2.9e-18, 30.09% id in 309 aa, and to Pseudomonas aeruginosa probable transmembrane sensor pa0471 SWALL:Q9I647 (EMBL:AE004485) (323 aa) fasta scores: E(): 8.9e-27, 32.58% id in 313 aa.
 
 
 0.834
ECA0814
Putative iron sensor protein; Similar to Escherichia coli protein FecR SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 4.1e-27, 33.01% id in 315 aa, and to Pseudomonas putida PupR protein SWALL:Q52209 (EMBL:X77918) (324 aa) fasta scores: E(): 3.3e-23, 29.9% id in 321 aa, and to Bordetella avium RhuR SWALL:Q8L1U8 (EMBL:AY095952) (307 aa) fasta scores: E(): 3.3e-17, 27.12% id in 317 aa.
 
 
 0.828
ECA1539
Similar to Pseudomonas aeruginosa probable transmembrane sensor pa3409 SWALL:Q9HYJ6 (EMBL:AE004762) (328 aa) fasta scores: E(): 2.2e-40, 42.68% id in 328 aa, and to Pseudomonas putida transmembrane sensor, putative pp4607 SWALL:AAN70180 (EMBL:AE016791) (326 aa) fasta scores: E(): 2.6e-25, 36.13% id in 321 aa.
 
 
 0.825
ECA0058
Transmembrane sensor; Similar to Escherichia coli protein FecR or b4292 SWALL:FECR_ECOLI (SWALL:P23485) (317 aa) fasta scores: E(): 3.1e-33, 36.04% id in 319 aa.
 
 
 0.822
hasR
TonB-dependent heme receptor; Similar to Serratia marcescens HasR protein SWALL:P72473 (EMBL:Y08983) (899 aa) fasta scores: E(): 2.1e-176, 62.03% id in 893 aa, and to Yersinia pestis putative TonB dependent receptor protein ypo3923 or hasr or y0313 SWALL:Q8ZA89 (EMBL:AJ414159) (830 aa) fasta scores: E(): 1.5e-86, 52.03% id in 786 aa.
 
  
 0.697
ECA0928
TonB-like protein; Similar to Salmonella typhimurium TonB protein SWALL:TONB_SALTY (SWALL:P25945) (242 aa) fasta scores: E(): 6.8e-09, 35.93% id in 192 aa, and to Escherichia coli TonB protein SWALL:TONB_ECOLI (SWALL:P02929) (239 aa) fasta scores: E(): 6.5e-07, 37.91% id in 182 aa.
  
  
 0.669
ECA1080
Hypothetical protein; No significant database matches.
       0.631
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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