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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1096Similar to Pseudomonas putida protein secretion ABC efflux system, membrane fusion protein pp0803 SWALL:AAN66428 (EMBL:AE016777) (394 aa) fasta scores: E(): 9.1e-67, 54.23% id in 378 aa, and to Escherichia coli O157:H7 putative membrane spanning export protein z0635 or ecs0544 SWALL:Q8XD11 (EMBL:AE005229) (391 aa) fasta scores: E(): 2.9e-66, 54.3% id in 372 aa. (389 aa)    
Predicted Functional Partners:
ECA1097
Similar to Pseudomonas putida protein secretion ABC efflux system, permease and ATP-binding protein pp0804 SWALL:AAN66429 (EMBL:AE016777) (722 aa) fasta scores: E(): 5.9e-111, 46.31% id in 691 aa, and to Salmonella typhi putative type i secretion protein, ATP-binding protein sty2877 SWALL:Q8Z4H9 (EMBL:AL627276) (718 aa) fasta scores: E(): 1.4e-103, 42.34% id in 692 aa.
 
 0.976
ECA1098
Putative type I secretion protein; Similar to Escherichia coli O157:H7 putative outer membrane export protein z0608 or ecs0540 SWALL:Q8XD20 (EMBL:AE005228) (451 aa) fasta scores: E(): 2.7e-75, 50.56% id in 439 aa, and to Ralstonia solanacearum putative outer membrane efflux transmembrane protein rsp1181 or rs06134 SWALL:Q8XQP1 (EMBL:AL646083) (483 aa) fasta scores: E(): 1.9e-23, 29.39% id in 398 aa.
 
 0.937
ECA3268
Putative toxin secretion ATP-binding protein; Similar to Actinobacillus pleuropneumoniae Rtx-I toxin determinant B Apxib or clyib or hlyib or appB SWALL:RT1B_ACTPL (SWALL:P26760) (707 aa) fasta scores: E(): 1.1e-55, 28.05% id in 695 aa, and to Pseudomonas putida toxin secretion ATP-binding protein pp0167 SWALL:AAN65800 (EMBL:AE016774) (718 aa) fasta scores: E(): 1.1e-188, 69.83% id in 706 aa, and to Pasteurella haemolytica leukotoxin secretion ATP-binding protein lktB SWALL:HLYB_PASHA (SWALL:P16532) (708 aa) fasta scores: E(): 1.1e-55, 27.84% id in 686 aa.
 
 0.904
aggA
Agglutination protein; Similar to Pseudomonas putida agglutination protein precursor AggA SWALL:Q52018 (EMBL:M64540) (452 aa) fasta scores: E(): 4e-73, 47.27% id in 440 aa, and to Vibrio cholerae agglutination protein vc1621 SWALL:Q9KRL6 (EMBL:AE004240) (445 aa) fasta scores: E(): 1.6e-51, 36.58% id in 421 aa.
 
 
 0.878
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.743
ECA3263
Putative exported protein; Similar to Pseudomonas putida conserved hypothetical protein pp0164 SWALL:AAN65797 (EMBL:AE016774) (213 aa) fasta scores: E(): 5.6e-51, 59.9% id in 207 aa, and to Vibrio vulnificus predicted periplasmic protein vv21126 SWALL:AAO08027 (EMBL:AE016812) (237 aa) fasta scores: E(): 2e-31, 44.87% id in 205 aa.
 
  
 0.708
hasD
Type I secretion ATP-binding protein; Similar to Pseudomonas fluorescens ABC protein HasD SWALL:Q9RHT2 (EMBL:AB023289) (580 aa) fasta scores: E(): 2.6e-129, 65.58% id in 584 aa, and to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 5.2e-113, 59.47% id in 570 aa. Also similar to ECA2783 (58.719% id. in 562 aa overlap).
  
 0.689
prtD
Similar to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 1.2e-155, 74.6% id in 575 aa. Also similar to ECA1536 (58.719% in 562 aa overlap.
  
 0.680
ECA3265
Hypothetical protein; No significant database matches.
 
     0.653
hasF
Similar to Pseudomonas fluorescens outer membrane protein HasF SWALL:Q9RHT0 (EMBL:AB023289) (442 aa) fasta scores: E(): 1.5e-85, 54.96% id in 433 aa, and to Erwinia chrysanthemi proteases secretion protein PrtF precursor prtF SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 2.1e-75, 48.82% id in 424 aa. Also similar to ECA2781 (48.956% identity in 431 aa overlap).
 
 
 0.584
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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