STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppnPConserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (94 aa)    
Predicted Functional Partners:
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.959
deoD
Purine nucleoside phosphorylase; Similar to Escherichia coli, and Escherichia coli O157:H7 purine nucleoside phosphorylase deoD or Pup or b4384 or z5986 or ecs5343 SWALL:DEOD_ECOLI (SWALL:P09743) (238 aa) fasta scores: E(): 2.1e-80, 89.07% id in 238 aa.
     
 0.959
ushA
Similar to Escherichia coli protein UshA precursor [includes: UDP-sugar hydrolase and 5'-nucleotidase] UshA or b0480 SWALL:USHA_ECOLI (SWALL:P07024) (550 aa) fasta scores: E(): 1.6e-157, 71.5% id in 551 aa; Belongs to the 5'-nucleotidase family.
     
 0.958
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
     
 0.957
ECA4103
Putative hydrolase; Similar to Yersinia pestis hypothetical protein ypo0141 or y3921 SWALL:AAM87465 (EMBL:AJ414141) (226 aa) fasta scores: E(): 4.7e-69, 76.57% id in 222 aa, and to Salmonella typhi putative hydrolase yrfg or sty4300 SWALL:Q8Z212 (EMBL:AL627281) (236 aa) fasta scores: E(): 7.2e-59, 65.31% id in 222 aa.
  
  
  0.953
add
Similar to Escherichia coli adenosine deaminase Add or b1623 SWALL:ADD_ECOLI (SWALL:P22333) (333 aa) fasta scores: E(): 2.2e-89, 71.77% id in 333 aa; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
     
 0.948
ECA0053
Putative phosphodiesterase; Similar to Vibrio cholerae 2`,3`-cyclic-nucleotide 2`-phosphodiesterase, putative vc2416 SWALL:Q9KPF2 (EMBL:AE004311) (634 aa) fasta scores: E(): 9.2e-161, 66.4% id in 634 aa; Belongs to the 5'-nucleotidase family.
     
 0.946
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.946
udk
Uridine kinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri uridine kinase Udk or b2066 or c2593 or z3234 or ecs2873 or sf2130 SWALL:URK_ECOLI (SWALL:P31218) (213 aa) fasta scores: E(): 3e-70, 87.32% id in 213 aa.
     
 0.946
cpdB
Similar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB or b4213 SWALL:CN16_ECOLI (SWALL:P08331) (647 aa) fasta scores: E(): 9.6e-198, 76.68% id in 639 aa; Belongs to the 5'-nucleotidase family.
     
 0.946
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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