Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
phoRSimilar to Escherichia coli phosphate regulon sensor protein PhoR or NmpB or b0400 SWALL:PHOR_ECOLI (SWALL:P08400) (431 aa) fasta scores: E(): 1e-129, 74.65% id in 430 aa, and to Yersinia pestis phosphate regulon sensor protein PhoR or ypo3204 or y0979 SWALL:AAM84560 (EMBL:AJ414155) (438 aa) fasta scores: E(): 9.4e-148, 83.06% id in 437 aa. (440 aa)    
Predicted Functional Partners:
phoB
Phosphate regulon response regulator; Similar to Escherichia coli, and Escherichia coli O157:H7 phosphate regulon transcriptional regulatory protein PhoB or b0399 or z0497 or ecs0449 SWALL:PHOB_ECOLI (SWALL:P08402) (229 aa) fasta scores: E(): 1.5e-81, 89.08% id in 229 aa, and to Yersinia pestis phosphate regulon transcriptional regulatory protein PhoB or ypo3205 SWALL:Q8ZC21 (EMBL:AJ414155) (229 aa) fasta scores: E(): 1.6e-84, 93.88% id in 229 aa.
 
 0.999
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
 
0.989
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 
0.985
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
   
 0.932
ECA1112
Similar to Yersinia pestis phosphate binding protein PstS or ypo3203 or y0980 SWALL:Q8ZC23 (EMBL:AJ414155) (354 aa) fasta scores: E(): 1.9e-76, 68.88% id in 286 aa, and to Pseudomonas aeruginosa phosphate binding protein psts or pa5369 SWALL:Q9Z9M3 (EMBL:AB017492) (323 aa) fasta scores: E(): 1.3e-62, 54.91% id in 295 aa.
 
  
 0.907
pehR
Two-component response regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PehR SWALL:Q9ZIN9 (EMBL:AF022772) (227 aa) fasta scores: E(): 1.5e-76, 91.26% id in 229 aa, and to Erwinia chrysanthemi PhoP protein phoP SWALL:CAD33237 (EMBL:AJ489252) (222 aa) fasta scores: E(): 7.2e-74, 87.83% id in 222 aa.
 
 0.858
phoU
Phosphate transport system protein; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.
 
  
 0.848
ompR
Two-component osmolarity response regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri transcriptional regulatory protein OmpR or OmpB or Kmt or b3405 or c4181 or z4760 or ecs4247 or stm3502 or sty4294 or t4004 or sf3424 SWALL:OMPR_ECOLI (SWALL:P03025) (239 aa) fasta scores: E(): 3.6e-91, 99.16% id in 239 aa.
 
 0.846
pstA
Phosphate ABC transporter permease protein; Similar to Pseudomonas aeruginosa a transmembrane component of the phosphate specific transport complex PstA SWALL:Q51545 (EMBL:D45195) (513 aa) fasta scores: E(): 8.4e-82, 50.99% id in 502 aa, and to Yersinia pestis putative phosphate transport system permease PstA or ypo2834 SWALL:Q8ZCX4 (EMBL:AJ414153) (570 aa) fasta scores: E(): 3.2e-124, 65.88% id in 551 aa.
 
  
 0.759
pstS
Phosphate-binding periplasmic protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
  
  
 0.759
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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