Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
proYSimilar to Salmonella typhimurium proline-specific permease ProY or stm0400 SWALL:PROY_SALTY (SWALL:P37460) (456 aa) fasta scores: E(): 7.4e-145, 82.78% id in 453 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 proline-specific permease ProY or b0402 or c0512 or z0500 or ecs0452 SWALL:PROY_ECOLI (SWALL:P77327) (457 aa) fasta scores: E(): 4.3e-145, 82.56% id in 453 aa. (458 aa)    
Predicted Functional Partners:
lacI
Similar to Escherichia coli lactose operon repressor LacI or b0345 SWALL:LACI_ECOLI (SWALL:P03023) (360 aa) fasta scores: E(): 1.6e-68, 52.11% id in 355 aa.
      
 0.664
brnQ
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
 
  
 0.663
rbsR
Ribose operon repressor; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribose operon repressor RbsR SWALL:AAN45274 (EMBL:M13169) (330 aa) fasta scores: E(): 2.9e-90, 68.99% id in 329 aa.
      
 0.571
purR
Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
      
 0.531
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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