STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (82 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
 
 0.998
ispA
Geranyltranstransferase; Similar to Escherichia coli geranyltranstransferase IspA or b0421 SWALL:ISPA_ECOLI (SWALL:P22939) (299 aa) fasta scores: E(): 4.8e-79, 71.76% id in 301 aa; Belongs to the FPP/GGPP synthase family.
  
  
 0.901
dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.808
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.652
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
   
    0.562
ispB
Octaprenyl-diphosphate synthase; Similar to Escherichia coli, and Shigella flexneri octaprenyl-diphosphate synthase IspB or Cel or b3187 or sf3227 SWALL:ISPB_ECOLI (SWALL:P19641) (323 aa) fasta scores: E(): 7.9e-100, 83.54% id in 322 aa; Belongs to the FPP/GGPP synthase family.
  
  
 0.558
recJ
Similar to Escherichia coli single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ECOLI (SWALL:P21893) (577 aa) fasta scores: E(): 3.5e-163, 71.03% id in 580 aa, and to Erwinia chrysanthemi single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ERWCH (SWALL:P39693) (575 aa) fasta scores: E(): 6.8e-178, 78.44% id in 580 aa.
  
  
 0.488
yajC
Putative membrane subunit of preprotein translocase; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
  
  
 0.480
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.463
KdtB
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
    0.459
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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