STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (296 aa)    
Predicted Functional Partners:
cyoD
Cytochrome O ubiquinol oxidase subunit IV; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri cytochrome o ubiquinol oxidase protein CyoD or b0429 or z0532 or ecs0483 or sf0370 SWALL:CYOD_ECOLI (SWALL:P18403) (109 aa) fasta scores: E(): 5.7e-26, 67.27% id in 110 aa.
 
 
 0.999
cyoC
Cytochrome o ubiquinol oxidase subunit III; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri cytochrome o ubiquinol oxidase subunit iii CyoC or b0430 or c0541 or sf0371 SWALL:CYOC_ECOLI (SWALL:P18402) (204 aa) fasta scores: E(): 2.7e-67, 78.53% id in 205 aa.
 
 
 0.999
cyoB
Cytochrome O ubiquinol oxidase subunit I; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ubiquinol oxidase polypeptide I CyoB or b0431 or c0542 or z0534 or ecs0485 SWALL:CYOB_ECOLI (SWALL:P18401) (663 aa) fasta scores: E(): 0, 82.95% id in 663 aa; Belongs to the heme-copper respiratory oxidase family.
 
 0.999
cyoA
Similar to Escherichia coli, and Escherichia coli O6 ubiquinol oxidase polypeptide ii precursor CyoA or b0432 or c0543 SWALL:CYOA_ECOLI (SWALL:P18400) (315 aa) fasta scores: E(): 2.4e-82, 67.18% id in 320 aa.
 
 
 0.998
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
 
 0.931
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
  
 0.635
ECA1138
Probable transporter; Similar to Yersinia pestis putative transporter ypo3169 or y1017 SWALL:AAM84598 (EMBL:AJ414155) (456 aa) fasta scores: E(): 3.6e-130, 78.41% id in 454 aa, and to Escherichia coli O6 hypothetical transport protein yajr or c0538 SWALL:AAN79016 (EMBL:AE016756) (520 aa) fasta scores: E(): 2.3e-119, 71.58% id in 454 aa.
 
   
 0.598
icd
Similar to Escherichia coli isocitrate dehydrogenase [NADP] Icd or IcdA or IcdE or b1136 SWALL:IDH_ECOLI (SWALL:P08200) (416 aa) fasta scores: E(): 1.7e-143, 88.01% id in 417 aa.
   
  
 0.557
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
  
 0.547
nuoB
NADH-quinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  
 0.540
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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