Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glnKNitrogen regulatory protein P-II; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri nitrogen regulatory protein P-II 2 GlnK or b0450 or c0568 or z0562 or ecs0504 or sf0395 SWALL:GLNK_ECOLI (SWALL:P38504) (112 aa) fasta scores: E(): 1.3e-34, 93.45% id in 107 aa; Belongs to the P(II) protein family. (107 aa)    
Predicted Functional Partners:
amtB
Probable ammonium transporter; Similar to Escherichia coli, and Escherichia coli O157:H7 probable ammonium transporter AmtB or b0451 or z0563 or ecs0505 SWALL:AMTB_ECOLI (SWALL:P37905) (428 aa) fasta scores: E(): 4.1e-125, 76.11% id in 427 aa.
 0.999
glnL
Nitrogen regulation two-component system, histidine kinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nitrogen regulation protein nr(II) GlnL or NtrB or GlnR SWALL:AAN45374 (EMBL:X05173) (349 aa) fasta scores: E(): 1.2e-108, 84.81% id in 349 aa.
  
 0.943
glnD
[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
 
 
 0.927
glnB
Nitrogen regulatory protein P-II; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri nitrogen regulatory protein P-II 1 SWALL:GLNB_ECOLI (SWALL:P05826) (112 aa) fasta scores: E(): 1e-37, 93.75% id in 112 aa; Belongs to the P(II) protein family.
    
 
 0.909
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
 
  
 0.757
argA
Amino-acid acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA or b2818 or c3412 or z4135 or ecs3675 SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.7e-149, 85.26% id in 441 aa, and to Yersinia pestis amino-acid acetyltransferase ArgA or ypo1022 or y3162 SWALL:Q8ZH86 (EMBL:AJ414146) (441 aa) fasta scores: E(): 1.5e-152, 88.43% id in 441 aa; Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.679
glnA
Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa.
 
 
 0.669
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
    
 
 0.669
araC
Similar to Erwinia chrysanthemi arabinose operon regulatory protein AraC SWALL:ARAC_ERWCH (SWALL:P07642) (310 aa) fasta scores: E(): 3.7e-129, 97.41% id in 309 aa, and to Escherichia coli, and Escherichia coli O157:H7 arabinose operon regulatory protein AraC or b0064 or z0073 or ecs0068 SWALL:ARAC_ECOLI (SWALL:P03021) (292 aa) fasta scores: E(): 1.2e-62, 57.09% id in 289 aa.
      
 0.461
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
  
  
 0.461
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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