STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acrAAcriflavine resistance protein A; Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein a precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 4e-103, 72.29% id in 397 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa)    
Predicted Functional Partners:
acrB
Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 80.84% id in 1039 aa.
 0.998
tolC
Similar to Escherichia coli outer membrane protein TolC precursor TolC or MtcB or MukA or RefI or b3035 SWALL:TOLC_ECOLI (SWALL:P02930) (495 aa) fasta scores: E(): 4.1e-124, 75.32% id in 466 aa, and to Erwinia chrysanthemi outer membrane protein TolC SWALL:Q93AG1 (EMBL:AF421372) (472 aa) fasta scores: E(): 2.3e-128, 77.89% id in 466 aa.
  
 0.935
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.920
acrD
Similar to Escherichia coli probable aminoglycoside efflux pump AcrD or b2470 SWALL:ACRD_ECOLI (SWALL:P24177) (1037 aa) fasta scores: E(): 0, 79.51% id in 1035 aa, and to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 64.87% id in 1042 aa.
 
 0.889
mexB
Similar to Pseudomonas aeruginosa multidrug resistance protein MexB or pa0426 SWALL:MEXB_PSEAE (SWALL:P52002) (1046 aa) fasta scores: E(): 1.9e-202, 50.82% id in 1037 aa, and to uncultured bacterium MexD protein mexD SWALL:Q8RSM1 (EMBL:AJ431260) (1047 aa) fasta scores: E(): 0, 64.14% id in 1043 aa.
 
 0.886
oprJ
Similar to Pseudomonas aeruginosa outer membrane protein OprJ precursor OprJ or pa4597 SWALL:OPRJ_PSEAE (SWALL:Q51397) (479 aa) fasta scores: E(): 1.2e-94, 57.82% id in 460 aa, and to Pseudomonas putida TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 2.4e-70, 45.14% id in 474 aa, and to Pseudomonas aeruginosa outer membrane protein oprm precursor oprm or oprk or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 1.9e-66, 46.78% id in 466 aa.
 
 
 0.849
acrR
Potential acrAB operon repressor; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri potential acrAB operon repressor AcrR or b0464 or c0582 or sf0409 SWALL:ACRR_ECOLI (SWALL:P34000) (215 aa) fasta scores: E(): 4.6e-49, 58.96% id in 212 aa.
     
 0.771
ECA2932
Similar to Ralstonia solanacearum putative drug efflux lipoprotein rsc3208 or rs02424 SWALL:Q8XUI0 (EMBL:AL646074) (486 aa) fasta scores: E(): 4e-119, 69.19% id in 487 aa, and to Xanthomonas campestris outer membrane protein oprn or xcc0419 SWALL:Q8PDC1 (EMBL:AE012139) (490 aa) fasta scores: E(): 9.1e-110, 65.09% id in 487 aa.
 
 
 0.688
mdtC
Similar to Escherichia coli multidrug transporter MdtC SWALL:BAC06609 (EMBL:AB089189) (1025 aa) fasta scores: E(): 0, 79.29% id in 1024 aa, and to Yersinia pestis acrb/acrd/acrf family membrane protein ypo2849 or y1384 SWALL:Q8ZCV9 (EMBL:AJ414154) (1024 aa) fasta scores: E(): 0, 79.68% id in 1019 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 0.649
mdtB
Similar to Escherichia coli multidrug transporter MdtB SWALL:BAC06608 (EMBL:AB089188) (1040 aa) fasta scores: E(): 0, 78.92% id in 1039 aa, and to Yersinia pestis acrb/acrd/acrf family membrane protein ypo2848 or y1385 SWALL:Q8ZCW0 (EMBL:AJ414154) (1052 aa) fasta scores: E(): 0, 80.73% id in 1038 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 0.614
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.