STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1197Similar to Yersinia pestis putative iron-sulphur binding protein ypo1212 or y2976 SWALL:Q8ZGR9 (EMBL:AJ414147) (85 aa) fasta scores: E(): 4.7e-17, 60% id in 80 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical ferredoxin-like protein yfae or b2236 or c2778 SWALL:YFAE_ECOLI (SWALL:P37910) (84 aa) fasta scores: E(): 2.2e-16, 58.02% id in 81 aa. (86 aa)    
Predicted Functional Partners:
nrdB
Similar to Escherichia coli, and Escherichia coli O157:H7 ribonucleoside-diphosphate reductase 1 beta chain NrdB or FtsB or b2235 or z3491 or ecs3118 SWALL:RIR2_ECOLI (SWALL:P00453) (375 aa) fasta scores: E(): 3.2e-139, 90.13% id in 375 aa.
 
  
 0.964
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.928
nrdA
Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.921
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 
 0.801
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.621
ECA3662
Putative cytochrome; Similar to Bacillus halodurans cytochrome P450 hydroxylase bh0579 SWALL:Q9KFA6 (EMBL:AP001509) (453 aa) fasta scores: E(): 2.2e-24, 26.19% id in 462 aa, and to Vicia sativa cytochrome P450 94a1 cyp94a1 or vagh111 SWALL:C941_VICSA (SWALL:O81117) (514 aa) fasta scores: E(): 2.2e-23, 25.88% id in 483 aa.
  
 0.615
nuoA
NADH-quinone oxidoreductase chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
   
 
 0.604
aegA
Anaerobically expressed oxidoreductase; Similar to Escherichia coli aega protein AegA or b2468 SWALL:AEGA_ECOLI (SWALL:P37127) (659 aa) fasta scores: E(): 3.7e-149, 61.43% id in 656 aa, and to Salmonella typhimurium putative oxidoreductase aega or stm2479 SWALL:Q8ZN79 (EMBL:AE008811) (653 aa) fasta scores: E(): 6e-147, 60.7% id in 649 aa.
   
 0.601
ECA1930
Similar to Yersinia pestis hypothetical protein Ypo2376 SWALL:Q8ZE14 (EMBL:AJ414152) (121 aa) fasta scores: E(): 8.5e-22, 58.76% id in 97 aa, and to Escherichia coli O157:H7 orf, hypothetical protein z2665 or ecs2358 SWALL:Q8X634 (EMBL:AE005388) (125 aa) fasta scores: E(): 1.4e-19, 53.84% id in 104 aa.
  
     0.595
nuoM
Similar to Escherichia coli, and Escherichia coli O157:H7 NADH-quinone oxidoreductase chain M NuoM or b2277 or z3536 or ecs3161 SWALL:NUOM_ECOLI (SWALL:P31978) (509 aa) fasta scores: E(): 8.2e-174, 86.18% id in 514 aa.
   
 
 0.592
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.