STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdBSimilar to Escherichia coli, and Escherichia coli O157:H7 ribonucleoside-diphosphate reductase 1 beta chain NrdB or FtsB or b2235 or z3491 or ecs3118 SWALL:RIR2_ECOLI (SWALL:P00453) (375 aa) fasta scores: E(): 3.2e-139, 90.13% id in 375 aa. (376 aa)    
Predicted Functional Partners:
nrdA
Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
nrdE
Ribonucleoside-diphosphate reductase 2 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.984
ECA1197
Similar to Yersinia pestis putative iron-sulphur binding protein ypo1212 or y2976 SWALL:Q8ZGR9 (EMBL:AJ414147) (85 aa) fasta scores: E(): 4.7e-17, 60% id in 80 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical ferredoxin-like protein yfae or b2236 or c2778 SWALL:YFAE_ECOLI (SWALL:P37910) (84 aa) fasta scores: E(): 2.2e-16, 58.02% id in 81 aa.
 
  
 0.964
cmk
Cytidylate kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 cytidylate kinase Cmk or MssA or b0910 or c1048 or z1256 or ecs0993 SWALL:KCY_ECOLI (SWALL:P23863) (227 aa) fasta scores: E(): 3.1e-66, 83.55% id in 225 aa.
    
 0.919
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.912
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.911
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.911
pykF
Pyruvate kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 pyruvate kinase I PykF or b1676 or z2704 or ecs2383 SWALL:KPY1_ECOLI (SWALL:P14178) (470 aa) fasta scores: E(): 4.4e-139, 84.68% id in 470 aa.
     
 0.908
pykA
Pyruvate kinase II; Similar to Escherichia coli pyruvate kinase ii PykA or b1854 SWALL:KPY2_ECOLI (SWALL:P21599) (479 aa) fasta scores: E(): 2.7e-156, 91.23% id in 479 aa.
     
 0.908
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.907
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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