Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA1206Probable transcriptional regulator; Similar to Agrobacterium tumefaciens hypothetical protein atu0863 atu0863 or agr_c_1578 SWALL:Q8UH22 (EMBL:AE009052) (143 aa) fasta scores: E(): 7e-27, 61.11% id in 126 aa, and to Bradyrhizobium japonicum transcriptional regulatory protein bll5105 SWALL:BAC50370 (EMBL:AP005953) (140 aa) fasta scores: E(): 9.7e-16, 50.47% id in 105 aa. (139 aa)    
Predicted Functional Partners:
ECA0371
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp0502 SWALL:AAN66130 (EMBL:AE016775) (147 aa) fasta scores: E(): 8e-26, 55.14% id in 136 aa. Note that there are no significant database matches to enterobacterial species.
  
     0.682
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
   
    0.534
ECA2235
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp2987 SWALL:AAN68595 (EMBL:AE016785) (187 aa) fasta scores: E(): 2.1e-33, 70.24% id in 121 aa, and to Rhizobium loti hypothetical protein Mll2592 SWALL:Q98I32 (EMBL:AP003000) (182 aa) fasta scores: E(): 6.4e-17, 49.56% id in 115 aa.
  
     0.494
rcsB
Two-component response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
  
    0.489
ECA1205
Similar to Yersinia pestis putative membrane protein ypo1221 or y2967 SWALL:Q8ZGR2 (EMBL:AJ414147) (384 aa) fasta scores: E(): 1.1e-95, 69.16% id in 373 aa, and to Bradyrhizobium japonicum Blr6253 protein blr6253 SWALL:BAC51518 (EMBL:AP005957) (436 aa) fasta scores: E(): 8.5e-59, 47.76% id in 381 aa.
       0.488
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
       0.476
ECA1207
Probable short chain dehydrogenase; Similar to Rhizobium meliloti putative sdr family dehydrogenase protein rb0962 or smb21384 SWALL:Q92UX3 (EMBL:AL603645) (247 aa) fasta scores: E(): 3e-56, 64.75% id in 244 aa, and to Agrobacterium tumefaciens oxidoreductase atu0864 or agr_c_1580 SWALL:Q8UH21 (EMBL:AE009052) (252 aa) fasta scores: E(): 2.7e-38, 48.38% id in 248 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.438
ECA0582
Putative plasmid-related protein; Similar to Escherichia coli PemK protein pemK SWALL:PEMK_ECOLI (SWALL:P13976) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa, and to Plasmid R100 plasmid stable inheritance protein pemK SWALL:BAA78898 (EMBL:AP000342) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa.
   
    0.413
chpA
Putative growth inhibitory protein; Similar to Escherichia coli, and Escherichia coli O157:H7 PemK-like protein 1 ChpA or MazF or ChpaK or b2782 or z4097 or ecs3642 SWALL:CHPA_ECOLI (SWALL:P33645) (111 aa) fasta scores: E(): 5.2e-31, 72.97% id in 111 aa, and to Deinococcus radiodurans ppgpp-regulated growth inhibitor chpa/mazf, putative dr0417 SWALL:Q9RX98 (EMBL:AE001901) (117 aa) fasta scores: E(): 5e-18, 48.21% id in 112 aa.
   
    0.413
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (12%) [HD]