STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menESimilar to Escherichia coli O-succinylbenzoic acid--CoA ligase MenE or b2260 SWALL:MENE_ECOLI (SWALL:P37353) (451 aa) fasta scores: E(): 1.5e-76, 53.43% id in 466 aa. (476 aa)    
Predicted Functional Partners:
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.999
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
 
 0.998
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
 0.993
menC
O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
 
  0.985
menC-2
N-acylamino acid racemase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
  0.978
menH
Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
 0.975
menD
Menaquinone biosynthesis protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
  
 0.953
cfa7
Similar to Pseudomonas syringae type I polyketide synthase Cfa7 SWALL:Q9Z3T8 (EMBL:AF098795) (2066 aa) fasta scores: E(): 0, 52.6% id in 2091 aa, and to Streptomyces coelicolor putative type I polyketide synthase sco6275 SWALL:CAD55506 (EMBL:AL939127) (4557 aa) fasta scores: E(): 3e-183, 44.33% id in 1845 aa.
  
 0.948
ECA2694
Putative polyketide synthetase; Similar to Amycolatopsis mediterranei peptide synthetase BpsD SWALL:Q939Y2 (EMBL:Y16952) (581 aa) fasta scores: E(): 2e-44, 32.34% id in 575 aa, and to Myxococcus xanthus Ta1 SWALL:Q9Z5F4 (EMBL:AJ006977) (2393 aa) fasta scores: E(): 4e-51, 32.97% id in 552 aa.
 
 0.815
menF
Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
 
   
 0.802
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (72%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.