close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
katAPutative catalase (partial); Partial CDS. Similar to the N-terminal regions of several catalases including Proteus mirabilis catalase KatA SWALL:CATA_PROMI (SWALL:P42321) (484 aa) fasta scores: E(): 0.072, 40.38% id in 52 aa, and to Yersinia pestis catalase KatA or ypo1207 or KatE or y2981 SWALL:Q8ZGS4 (EMBL:AJ414147) (480 aa) fasta scores: E(): 0.013, 42.3% id in 52 aa. (75 aa)    
Predicted Functional Partners:
ECA1217
Putative exported protein; Similar to Yersinia pestis hypothetical protein y2980 SWALL:Q8D012 (EMBL:AE013899) (180 aa) fasta scores: E(): 9.3e-31, 47.77% id in 180 aa, and to Escherichia coli hypothetical protein yfaz precursor yfaz or b2250 SWALL:YFAZ_ECOLI (SWALL:P76471) (180 aa) fasta scores: E(): 4.1e-29, 46.11% id in 180 aa.
       0.479
djlA
Putative DnaJ-like heat shock protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
      
 0.473
hupA
DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
      
 0.471
accC
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
      
 0.471
argA
Amino-acid acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA or b2818 or c3412 or z4135 or ecs3675 SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.7e-149, 85.26% id in 441 aa, and to Yersinia pestis amino-acid acetyltransferase ArgA or ypo1022 or y3162 SWALL:Q8ZH86 (EMBL:AJ414146) (441 aa) fasta scores: E(): 1.5e-152, 88.43% id in 441 aa; Belongs to the acetyltransferase family. ArgA subfamily.
      
 0.471
ECA1059
Putative integrase; Similar to Escherichia coli O157:H7 putative site specific recombinase ecs3512 SWALL:Q8X3D8 (EMBL:AP002562) (401 aa) fasta scores: E(): 3.9e-44, 35.44% id in 395 aa, and to Staphylococcus aureus transposase a from transposon tn554 SWALL:TNPA_STAAM (SWALL:P06696) (361 aa) fasta scores: E(): 0.039, 23.1% id in 303 aa.
      
 0.471
ECA1065
Hypothetical protein; No significant database matches.
      
 0.471
cyoC
Cytochrome o ubiquinol oxidase subunit III; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri cytochrome o ubiquinol oxidase subunit iii CyoC or b0430 or c0541 or sf0371 SWALL:CYOC_ECOLI (SWALL:P18402) (204 aa) fasta scores: E(): 2.7e-67, 78.53% id in 205 aa.
      
 0.471
ECA1166
Similar to Yersinia pestis hypothetical protein ypo3137 or y1047 SWALL:Q8ZC84 (EMBL:AJ414155) (122 aa) fasta scores: E(): 8.8e-36, 74.59% id in 122 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein ybaj or b0461 or c0579 or z0574 or ecs0514 SWALL:YBAJ_ECOLI (SWALL:P37611) (124 aa) fasta scores: E(): 1.4e-26, 60.83% id in 120 aa.
      
 0.471
hypD
Similar to Escherichia coli hydrogenase isoenzymes formation protein HypD or b2729 SWALL:HYPD_ECOLI (SWALL:P24192) (373 aa) fasta scores: E(): 2.4e-119, 76.55% id in 371 aa; Belongs to the HypD family.
      
 0.471
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (80%) [HD]