STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrPTyrosine-specific transport protein; Similar to Escherichia coli, and Shigella flexneri tyrosine-specific transport protein TyrP or b1907 or sf1953 SWALL:TYRP_ECOLI (SWALL:P18199) (403 aa) fasta scores: E(): 3.6e-112, 73.13% id in 402 aa. (402 aa)    
Predicted Functional Partners:
menC
O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
  
     0.577
uhpC
Similar to Escherichia coli regulatory protein UhpC or b3667 SWALL:UHPC_ECOLI (SWALL:P09836) (439 aa) fasta scores: E(): 3.6e-99, 53.34% id in 433 aa, and to Yersinia pestis putative regulatory protein UhpC or ypo4007 SWALL:Q8ZA15 (EMBL:AJ414160) (443 aa) fasta scores: E(): 3.8e-103, 56.11% id in 417 aa.
  
     0.540
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
  
   
 0.525
dcuC
Anaerobic C4-dicarboxylate transporter; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri anaerobic c4-dicarboxylate transporter DcuC or b0621 or z0766 or ecs0660 or sf0659 SWALL:DCUC_ECOLI (SWALL:Q47134) (461 aa) fasta scores: E(): 3.1e-137, 81.25% id in 448 aa.
  
   
 0.522
ECA1474
Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa.
  
     0.479
ECA0692
Similar to Yersinia pestis putative membrane protein ypo3510 SWALL:AAM84262 (EMBL:AJ414157) (328 aa) fasta scores: E(): 3e-95, 78.77% id in 311 aa, and to Salmonella typhi putative membrane protein sty3481 SWALL:Q8Z3H0 (EMBL:AL627278) (321 aa) fasta scores: E(): 1.3e-92, 77.24% id in 312 aa.
  
 
   0.464
frdC
Fumarate reductase 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
     0.445
ECA3037
Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yfbu or stm2335 or sty2565 SWALL:Q8XGJ0 (EMBL:AE008805) (164 aa) fasta scores: E(): 4.1e-58, 87.19% id in 164 aa, and to Yersinia pestis hypothetical protein Ypo2563 SWALL:Q8ZDJ9 (EMBL:AJ414152) (164 aa) fasta scores: E(): 8.8e-58, 82.92% id in 164 aa; Belongs to the UPF0304 family.
  
     0.437
hcr
Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa.
  
     0.425
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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