STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1220Similar to Yersinia pestis putative thioredoxin ypo3082 or y1097 SWALL:Q8ZCB1 (EMBL:AJ414155) (289 aa) fasta scores: E(): 1e-69, 71.93% id in 285 aa, and to Escherichia coli hypothetical protein ybbn or b0492 SWALL:YBBN_ECOLI (SWALL:P77395) (284 aa) fasta scores: E(): 3.8e-68, 70.96% id in 279 aa. (286 aa)    
Predicted Functional Partners:
gor
Similar to Escherichia coli glutathione reductase Gor SWALL:GSHR_ECOLI (SWALL:P06715) (450 aa) fasta scores: E(): 3.8e-155, 86.66% id in 450 aa and to to Yersinia pestis glutathione reductase Gor SWALL:Q8ZA43 (EMBL:AJ414160) (450 aa) fasta scores: E(): 7.8e-158, 88.66% id in 450 aa.
 
 
 0.964
hslV
ATP-dependent protease (heat shock protein); Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.922
grpE
Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]
  
  
 0.914
hslU
ATP-dependent Hsl protease ATP-binding subunit (heat shock protein); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
  
 
 0.911
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.874
fxsA
Suppressor of F plamsid exlusion of phage T7; Similar to Escherichia coli FxsA protein FxsA or b4140 SWALL:FXSA_ECOLI (SWALL:P37147) (158 aa) fasta scores: E(): 1.3e-38, 68.35% id in 158 aa.
   
    0.771
ECA2649
Thioredoxin reductase.
  
 0.751
htpG
Chaperone protein; Molecular chaperone. Has ATPase activity.
  
 
 0.711
rhs
Putative RHS protein; Similar to Photorhabdus luminescens Rhs Rhs-corE SWALL:AAN64198 (EMBL:AY144117) (1469 aa) fasta scores: E(): 3.1e-128, 41.64% id in 1395 aa, and to Ralstonia solanacearum putative RHS-related transmembrane protein rsp1137 or rs05482 SWALL:Q8XQT2 (EMBL:AL646083) (1517 aa) fasta scores: E(): 3e-74, 32.03% id in 1330 aa.
    
   0.688
ECA4278
Rhs-family protein; Similar to Photorhabdus luminescens Rhs Rhs-corE SWALL:AAN64198 (EMBL:AY144117) (1469 aa) fasta scores: E(): 3.6e-127, 42.61% id in 1361 aa, and to Escherichia coli O157:H7 rhs core protein with extension ecs0605 SWALL:Q8X2J4 (EMBL:AP002552) (1616 aa) fasta scores: E(): 3.9e-80, 37.61% id in 1361 aa.
    
   0.688
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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