Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hybAHydrogenase-2 operon protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-2 operon protein hyba precursor HybA or b2996 or z4350 or ecs3881 or sf3043 SWALL:HYBA_ECOLI (SWALL:P37179) (328 aa) fasta scores: E(): 4.3e-93, 70.23% id in 336 aa. (336 aa)    
Predicted Functional Partners:
hybB
Similar to Escherichia coli probable Ni/Fe-hydrogenase 2 B-type cytochrome subunit hybb or b2995 SWALL:HYBB_ECOLI (SWALL:P37180) (392 aa) fasta scores: E(): 8.4e-123, 73.69% id in 384 aa.
 0.998
hybO
Hydrogenase-2 small subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hydrogenase-2 small chain precursor hybO or b2997 or c3734 or z4351 or ecs3882 SWALL:MBHT_ECOLI (SWALL:Q46847) (372 aa) fasta scores: E(): 2.9e-121, 80.75% id in 369 aa.
 
 
 0.992
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.979
hybC
Hydrogenase-2 large subunit; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-2 large chain precursor HybC or b2994 or z4348 or ecs3879 or sf3041 SWALL:MBHM_ECOLI (SWALL:P37181) (566 aa) fasta scores: E(): 2e-178, 73.85% id in 566 aa; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.964
fdnG
Similar to Escherichia coli formate dehydrogenase, nitrate-inducible, major subunit FdnG or b1474 SWALL:FDNG_ECOLI (SWALL:P24183) (1015 aa) fasta scores: E(): 0, 69.75% id in 1015 aa.
 
 0.936
hybD
Similar to Escherichia coli hydrogenase 2 maturation protease HybD or b2993 SWALL:HYBD_ECOLI (SWALL:P37182) (164 aa) fasta scores: E(): 1.7e-36, 67.7% id in 161 aa.
 
  
 0.913
fdnI
Formate dehydrogenase, nitrate-inducible, cytochrome b556; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri formate dehydrogenase, nitrate-inducible, cytochrome b556 FdnI or b1476 or z2234 or ecs2080 or sf1749 SWALL:FDNI_ECOLI (SWALL:P24185) (217 aa) fasta scores: E(): 7.5e-70, 78.19% id in 211 aa.
 
 0.886
ECA1009
Similar to Rhodobacter sphaeroides biotin sulfoxide reductase SWALL:BISC_RHOSH (SWALL:P54934) (744 aa) fasta scores: E(): 6.3e-130, 48.13% id in 725 aa, and to Escherichia coli biotin sulfoxide reductase bisc or b3551 SWALL:BISC_ECOLI (SWALL:P20099) (777 aa) fasta scores: E(): 8.5e-72, 39.01% id in 751 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.881
hybE
Hydrogenase-2 component protein; Similar to Escherichia coli, and Escherichia coli O6 hydrogenase-2 operon protein HybE or b2992 or c3729 SWALL:HYBE_ECOLI (SWALL:P37183) (162 aa) fasta scores: E(): 1.3e-27, 48.05% id in 154 aa.
 
    0.878
hyfA
Similar to Escherichia coli hydrogenase-4 component A HyfA or b2481 SWALL:HYFA_ECOLI (SWALL:P23481) (205 aa) fasta scores: E(): 4.1e-36, 49.75% id in 207 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri formate hydrogenlyase subunit 2 hycb or hevb or b2724 or c3284 or sf2741 SWALL:HYCB_ECOLI (SWALL:P16428) (203 aa) fasta scores: E(): 5.2e-37, 50.24% id in 205 aa.
 
  
  0.738
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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