Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
fdhFSimilar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (716 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 0.989
hyfG
Similar to Escherichia coli hydrogenase-4 component G HyfG or b2487 SWALL:HYFG_ECOLI (SWALL:P77329) (555 aa) fasta scores: E(): 3.1e-128, 78.03% id in 569 aa.
 
 
 0.983
napF
Ferredoxin-type protein; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.
   
 0.983
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 0.963
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
 0.928
hyfA
Similar to Escherichia coli hydrogenase-4 component A HyfA or b2481 SWALL:HYFA_ECOLI (SWALL:P23481) (205 aa) fasta scores: E(): 4.1e-36, 49.75% id in 207 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri formate hydrogenlyase subunit 2 hycb or hevb or b2724 or c3284 or sf2741 SWALL:HYCB_ECOLI (SWALL:P16428) (203 aa) fasta scores: E(): 5.2e-37, 50.24% id in 205 aa.
 
 0.922
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 0.902
hydN
Electron transport protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 electron transport protein HydN or b2713 or c3269 or z4021 or ecs3569 SWALL:HYDN_ECOLI (SWALL:P30132) (175 aa) fasta scores: E(): 2.2e-48, 71.09% id in 173 aa.
 
  0.892
hoxN
Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family.
     
 0.881
fdhD
Putative formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 
 0.876
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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