STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hoxNSimilar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. (327 aa)    
Predicted Functional Partners:
fdhF
Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.881
hypF
Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
       0.815
ECA3888
Similar to Yersinia pestis hypothetical protein Ypo0462 SWALL:Q8ZIN3 (EMBL:AJ414142) (258 aa) fasta scores: E(): 5.4e-78, 79.76% id in 257 aa, and to Escherichia coli O6 protein yaaa or c0010 SWALL:AAN78510 (EMBL:AE016755) (258 aa) fasta scores: E(): 1.7e-77, 80.15% id in 257 aa; Belongs to the UPF0246 family.
 
      0.668
hydN
Electron transport protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 electron transport protein HydN or b2713 or c3269 or z4021 or ecs3569 SWALL:HYDN_ECOLI (SWALL:P30132) (175 aa) fasta scores: E(): 2.2e-48, 71.09% id in 173 aa.
       0.652
hyfA
Similar to Escherichia coli hydrogenase-4 component A HyfA or b2481 SWALL:HYFA_ECOLI (SWALL:P23481) (205 aa) fasta scores: E(): 4.1e-36, 49.75% id in 207 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri formate hydrogenlyase subunit 2 hycb or hevb or b2724 or c3284 or sf2741 SWALL:HYCB_ECOLI (SWALL:P16428) (203 aa) fasta scores: E(): 5.2e-37, 50.24% id in 205 aa.
     
 0.631
ECA1450
Putative protease; Similar to Bacillus subtilis kumamolysin kumA SWALL:Q8RR56 (EMBL:AB070740) (572 aa) fasta scores: E(): 6.7e-73, 42.67% id in 539 aa, and to Alicyclobacillus sendaienensis collagenolytic serine-carboxyl proteinase precursor AscP SWALL:BAC41257 (EMBL:AB085855) (553 aa) fasta scores: E(): 3.3e-72, 43.59% id in 539 aa.
  
     0.611
hyfB
Hydrogenase-4 component B; Similar to Escherichia coli hydrogenase-4 component B HyfB or b2482 SWALL:HYFB_ECOLI (SWALL:P23482) (672 aa) fasta scores: E(): 5.6e-158, 61.81% id in 673 aa.
     
 0.567
hyfC
Similar to Escherichia coli hydrogenase-4 component C HyfC or b2483 SWALL:HYFC_ECOLI (SWALL:P77858) (315 aa) fasta scores: E(): 4.9e-85, 73.35% id in 304 aa.
     
 0.566
hyfF
Hydrogenase-4 component F; Similar to Escherichia coli hydrogenase-4 component F HyfF or b2486 SWALL:HYFF_ECOLI (SWALL:P77437) (526 aa) fasta scores: E(): 1.1e-133, 67.12% id in 508 aa.
     
 0.559
hyfE
Hydrogenase-4 component E; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-4 component E HyfE or b2485 or z3745 or ecs3347 or sf2528 SWALL:HYFE_ECOLI (SWALL:P77524) (216 aa) fasta scores: E(): 4.6e-50, 63.42% id in 216 aa.
     
 0.559
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.