| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA1450 | hoxN | ECA1450 | ECA1252 | Putative protease; Similar to Bacillus subtilis kumamolysin kumA SWALL:Q8RR56 (EMBL:AB070740) (572 aa) fasta scores: E(): 6.7e-73, 42.67% id in 539 aa, and to Alicyclobacillus sendaienensis collagenolytic serine-carboxyl proteinase precursor AscP SWALL:BAC41257 (EMBL:AB085855) (553 aa) fasta scores: E(): 3.3e-72, 43.59% id in 539 aa. | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | 0.611 |
| ECA3888 | hoxN | ECA3888 | ECA1252 | Similar to Yersinia pestis hypothetical protein Ypo0462 SWALL:Q8ZIN3 (EMBL:AJ414142) (258 aa) fasta scores: E(): 5.4e-78, 79.76% id in 257 aa, and to Escherichia coli O6 protein yaaa or c0010 SWALL:AAN78510 (EMBL:AE016755) (258 aa) fasta scores: E(): 1.7e-77, 80.15% id in 257 aa; Belongs to the UPF0246 family. | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | 0.668 |
| fdhF | hoxN | ECA1250 | ECA1252 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | 0.892 |
| fdhF | hybO | ECA1250 | ECA1225 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hydrogenase-2 small subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hydrogenase-2 small chain precursor hybO or b2997 or c3734 or z4351 or ecs3882 SWALL:MBHT_ECOLI (SWALL:Q46847) (372 aa) fasta scores: E(): 2.9e-121, 80.75% id in 369 aa. | 0.595 |
| fdhF | hydN | ECA1250 | ECA1249 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Electron transport protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 electron transport protein HydN or b2713 or c3269 or z4021 or ecs3569 SWALL:HYDN_ECOLI (SWALL:P30132) (175 aa) fasta scores: E(): 2.2e-48, 71.09% id in 173 aa. | 0.898 |
| fdhF | hyfA | ECA1250 | ECA1247 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Similar to Escherichia coli hydrogenase-4 component A HyfA or b2481 SWALL:HYFA_ECOLI (SWALL:P23481) (205 aa) fasta scores: E(): 4.1e-36, 49.75% id in 207 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri formate hydrogenlyase subunit 2 hycb or hevb or b2724 or c3284 or sf2741 SWALL:HYCB_ECOLI (SWALL:P16428) (203 aa) fasta scores: E(): 5.2e-37, 50.24% id in 205 aa. | 0.924 |
| fdhF | hyfC | ECA1250 | ECA1245 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Similar to Escherichia coli hydrogenase-4 component C HyfC or b2483 SWALL:HYFC_ECOLI (SWALL:P77858) (315 aa) fasta scores: E(): 4.9e-85, 73.35% id in 304 aa. | 0.828 |
| fdhF | hyfE | ECA1250 | ECA1243 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hydrogenase-4 component E; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-4 component E HyfE or b2485 or z3745 or ecs3347 or sf2528 SWALL:HYFE_ECOLI (SWALL:P77524) (216 aa) fasta scores: E(): 4.6e-50, 63.42% id in 216 aa. | 0.627 |
| fdhF | hyfF | ECA1250 | ECA1242 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hydrogenase-4 component F; Similar to Escherichia coli hydrogenase-4 component F HyfF or b2486 SWALL:HYFF_ECOLI (SWALL:P77437) (526 aa) fasta scores: E(): 1.1e-133, 67.12% id in 508 aa. | 0.754 |
| fdhF | hypF | ECA1250 | ECA1251 | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.805 |
| hoxN | ECA1450 | ECA1252 | ECA1450 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Putative protease; Similar to Bacillus subtilis kumamolysin kumA SWALL:Q8RR56 (EMBL:AB070740) (572 aa) fasta scores: E(): 6.7e-73, 42.67% id in 539 aa, and to Alicyclobacillus sendaienensis collagenolytic serine-carboxyl proteinase precursor AscP SWALL:BAC41257 (EMBL:AB085855) (553 aa) fasta scores: E(): 3.3e-72, 43.59% id in 539 aa. | 0.611 |
| hoxN | ECA3888 | ECA1252 | ECA3888 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Similar to Yersinia pestis hypothetical protein Ypo0462 SWALL:Q8ZIN3 (EMBL:AJ414142) (258 aa) fasta scores: E(): 5.4e-78, 79.76% id in 257 aa, and to Escherichia coli O6 protein yaaa or c0010 SWALL:AAN78510 (EMBL:AE016755) (258 aa) fasta scores: E(): 1.7e-77, 80.15% id in 257 aa; Belongs to the UPF0246 family. | 0.668 |
| hoxN | fdhF | ECA1252 | ECA1250 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Similar to Escherichia coli formate dehydrogenase H FdhF or b4079 SWALL:FDHF_ECOLI (SWALL:P07658) (715 aa) fasta scores: E(): 2.2e-193, 64.61% id in 715 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.892 |
| hoxN | hybO | ECA1252 | ECA1225 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Hydrogenase-2 small subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hydrogenase-2 small chain precursor hybO or b2997 or c3734 or z4351 or ecs3882 SWALL:MBHT_ECOLI (SWALL:Q46847) (372 aa) fasta scores: E(): 2.9e-121, 80.75% id in 369 aa. | 0.599 |
| hoxN | hydN | ECA1252 | ECA1249 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Electron transport protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 electron transport protein HydN or b2713 or c3269 or z4021 or ecs3569 SWALL:HYDN_ECOLI (SWALL:P30132) (175 aa) fasta scores: E(): 2.2e-48, 71.09% id in 173 aa. | 0.637 |
| hoxN | hyfA | ECA1252 | ECA1247 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Similar to Escherichia coli hydrogenase-4 component A HyfA or b2481 SWALL:HYFA_ECOLI (SWALL:P23481) (205 aa) fasta scores: E(): 4.1e-36, 49.75% id in 207 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri formate hydrogenlyase subunit 2 hycb or hevb or b2724 or c3284 or sf2741 SWALL:HYCB_ECOLI (SWALL:P16428) (203 aa) fasta scores: E(): 5.2e-37, 50.24% id in 205 aa. | 0.663 |
| hoxN | hyfC | ECA1252 | ECA1245 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Similar to Escherichia coli hydrogenase-4 component C HyfC or b2483 SWALL:HYFC_ECOLI (SWALL:P77858) (315 aa) fasta scores: E(): 4.9e-85, 73.35% id in 304 aa. | 0.594 |
| hoxN | hyfE | ECA1252 | ECA1243 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Hydrogenase-4 component E; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-4 component E HyfE or b2485 or z3745 or ecs3347 or sf2528 SWALL:HYFE_ECOLI (SWALL:P77524) (216 aa) fasta scores: E(): 4.6e-50, 63.42% id in 216 aa. | 0.572 |
| hoxN | hyfF | ECA1252 | ECA1242 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Hydrogenase-4 component F; Similar to Escherichia coli hydrogenase-4 component F HyfF or b2486 SWALL:HYFF_ECOLI (SWALL:P77437) (526 aa) fasta scores: E(): 1.1e-133, 67.12% id in 508 aa. | 0.572 |
| hoxN | hypF | ECA1252 | ECA1251 | Similar to Alcaligenes eutrophus high-affinity nickel transport protein HoxN SWALL:HOXN_ALCEU (SWALL:P23516) (351 aa) fasta scores: E(): 1.2e-68, 54.63% id in 324 aa, and to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HupN or bll6949 SWALL:HUPN_BRAJA (SWALL:Q45247) (381 aa) fasta scores: E(): 1.8e-62, 51.91% id in 314 aa; Belongs to the NiCoT transporter (TC 2.A.52) family. | Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.801 |