STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bepAPutative exported protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (487 aa)    
Predicted Functional Partners:
ECA1258
Similar to Yersinia pestis putative arsenate reductase ypo3070 SWALL:Q8ZCC2 (EMBL:AJ414155) (118 aa) fasta scores: E(): 2.4e-28, 72.8% id in 114 aa, and to Escherichia coli protein yfgd or b2495 SWALL:YFGD_ECOLI (SWALL:P76569) (119 aa) fasta scores: E(): 2.2e-27, 71.05% id in 114 aa.
  
  
 0.803
bcp
Bacterioferritin comigratory protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri bacterioferritin comigratory protein Bcp or b2480 or c3008 or z3739 or ecs3342 or sf2523 SWALL:BCP_ECOLI (SWALL:P23480) (156 aa) fasta scores: E(): 2.4e-51, 88.23% id in 153 aa.
  
    0.551
imp
Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
  
 0.551
ECA0170
Putative exported peptidase; Similar to Yersinia pestis putative membrane protein y0078 SWALL:AAM83673 (EMBL:AE013608) (456 aa) fasta scores: E(): 2.5e-78, 71.87% id in 416 aa, and to Salmonella typhi hypothetical protein Sty4090 SWALL:Q8Z2F1 (EMBL:AL627280) (427 aa) fasta scores: E(): 9.5e-72, 67.49% id in 403 aa, and to Escherichia coli hypothetical protein YibP SWALL:YIBP_ECOLI (SWALL:P37690) (419 aa) fasta scores: E(): 3.5e-71, 66.5% id in 403 aa.
 
 
 
 0.545
ECA4182
Similar to Yersinia pestis hypothetical protein ypo3844 or y0386 SWALL:Q8ZAF8 (EMBL:AJ414159) (234 aa) fasta scores: E(): 1.8e-68, 73.93% id in 234 aa, and to Salmonella typhi hypothetical protein Sty3611 SWALL:Q8Z3A7 (EMBL:AL627279) (235 aa) fasta scores: E(): 4.6e-60, 64.68% id in 235 aa.
  
    0.534
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
  
    0.507
bspA
Putative mechanosensitive ion channel; Similar to Erwinia chrysanthemi BspA protein precursor BspA SWALL:Q9EV03 (EMBL:AJ251781) (1106 aa) fasta scores: E(): 0, 77.97% id in 1108 aa, and to Yersinia pestis putative membrane transport protein ypo0363 or y0619 SWALL:AAM84207 (EMBL:AJ414142) (1119 aa) fasta scores: E(): 0, 71.54% id in 1114 aa.
 
 
 
 0.506
ECA0388
Putative peptidase; Similar to Yersinia pestis m48 peptidase family protein ypo0398 SWALL:AAM87329 (EMBL:AJ414142) (348 aa) fasta scores: E(): 4.5e-79, 59.88% id in 344 aa.
  
     0.503
gcvR
Similar to Escherichia coli, and Shigella flexneri glycine cleavage system transcriptional repressor GcvR or b2479 or sf2522 SWALL:GCVR_ECOLI (SWALL:P23483) (189 aa) fasta scores: E(): 9.9e-53, 75.97% id in 179 aa.
 
    0.487
rseB
sigma-E factor regulatory protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri sigma-E factor regulatory protein RseB precursor RseB or b2571 or z3853 or ecs3437 or sf2633 SWALL:RSEB_ECOLI (SWALL:P46186) (318 aa) fasta scores: E(): 3.1e-69, 57.36% id in 319 aa.
  
     0.480
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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