Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
gcvRSimilar to Escherichia coli, and Shigella flexneri glycine cleavage system transcriptional repressor GcvR or b2479 or sf2522 SWALL:GCVR_ECOLI (SWALL:P23483) (189 aa) fasta scores: E(): 9.9e-53, 75.97% id in 179 aa. (183 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.819
bcp
Bacterioferritin comigratory protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri bacterioferritin comigratory protein Bcp or b2480 or c3008 or z3739 or ecs3342 or sf2523 SWALL:BCP_ECOLI (SWALL:P23480) (156 aa) fasta scores: E(): 2.4e-51, 88.23% id in 153 aa.
  
    0.784
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
  0.744
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.697
nlpB
Lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.621
ECA1310
Similar to Yersinia pestis hypothetical protein Ypo2611 SWALL:Q8ZDF7 (EMBL:AJ414153) (160 aa) fasta scores: E(): 3.3e-46, 76.87% id in 160 aa, and to Salmonella typhimurium putative cytoplasmic protein ybel or stm0653 SWALL:Q8ZQZ2 (EMBL:AE008726) (157 aa) fasta scores: E(): 2.3e-42, 71.25% id in 160 aa.
  
     0.614
ftsL
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.576
ECA3608
Similar to Yersinia pestis hypothetical protein ypo3533 or y0650 SWALL:Q8ZB86 (EMBL:AJ414157) (246 aa) fasta scores: E(): 7.2e-27, 42.8% id in 250 aa, and to Shigella flexneri orf, conserved hypothetical protein ytfb or sf4280 SWALL:AAN45698 (EMBL:AE015436) (193 aa) fasta scores: E(): 9e-23, 43.93% id in 198 aa.
  
     0.570
rseB
sigma-E factor regulatory protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri sigma-E factor regulatory protein RseB precursor RseB or b2571 or z3853 or ecs3437 or sf2633 SWALL:RSEB_ECOLI (SWALL:P46186) (318 aa) fasta scores: E(): 3.1e-69, 57.36% id in 319 aa.
  
     0.567
smg
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri protein Smg or b3284 or sf3316 SWALL:SMG_ECOLI (SWALL:P30853) (157 aa) fasta scores: E(): 6.6e-48, 76.43% id in 157 aa, and to Salmonella typhimurium, and Salmonella typhi Smg protein homolog Smg or stm3404 or sty4393 or t4100 SWALL:SMG_SALTY (SWALL:Q8XFK8) (157 aa) fasta scores: E(): 8.8e-49, 78.34% id in 157 aa; Belongs to the Smg family.
  
    0.557
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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