STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1267Thioredoxin; The N-terminal region of this CDS is similar to several thioredoxinx including Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri thioredoxin 1 SWALL:THIO_ECOLI (SWALL:P00274) (108 aa) fasta scores: E(): 1.7e-14, 46.22% id in 106 aa, and to Thiobacillus ferrooxidans thioredoxin trxA SWALL:THIO_THIFE (SWALL:P52233) (108 aa) fasta scores: E(): 2.3e-14, 45.79% id in 107 aa. (421 aa)    
Predicted Functional Partners:
ECA2649
Thioredoxin reductase.
 
 
 0.809
katB
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
    
 
 0.635
dps
DNA protection during starvation protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
   
  
 0.604
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
    
 
 0.593
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.591
tldD-2
Putative suppressor of the inhibitory activity of the carbon storage regulator CsrA; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri TldD protein or b3244 or c3999 or sf3283 SWALL:TLDD_ECOLI (SWALL:P46473) (481 aa) fasta scores: E(): 6e-95, 54.66% id in 472 aa. Also similar to ECA0273 (55.297% id. in 472 aa overlap).
       0.584
grxA
Glutaredoxin 1; Similar to Escherichia coli, and Shigella flexneri glutaredoxin 1 GrxA or Grx or b0849 or sf0802 SWALL:GLR1_ECOLI (SWALL:P00277) (85 aa) fasta scores: E(): 6e-21, 69.88% id in 83 aa.
  
  
 0.582
fur
Ferric uptake regulation protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ferric uptake regulation protein Fur or b0683 or c0770 or z0831 or ecs0714 SWALL:FUR_ECOLI (SWALL:P06975) (148 aa) fasta scores: E(): 9.2e-52, 91.09% id in 146 aa; Belongs to the Fur family.
  
 
 0.559
tnpA
Transposase transposon tn1721 (partial); Partial CDS. Similar to the C-terminal regions of many transposases including Escherichia coli transposase for transposon Tn1721 TnpA SWALL:TNP9_ECOLI (SWALL:P51565) (988 aa) fasta scores: E(): 6.4e-25, 83.75% id in 80 aa.
      
 0.540
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
    
 
 0.535
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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