STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ECA1267Thioredoxin; The N-terminal region of this CDS is similar to several thioredoxinx including Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri thioredoxin 1 SWALL:THIO_ECOLI (SWALL:P00274) (108 aa) fasta scores: E(): 1.7e-14, 46.22% id in 106 aa, and to Thiobacillus ferrooxidans thioredoxin trxA SWALL:THIO_THIFE (SWALL:P52233) (108 aa) fasta scores: E(): 2.3e-14, 45.79% id in 107 aa. (421 aa)    
Predicted Functional Partners:
ECA2649
Thioredoxin reductase.
 
 0.909
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
    
 
 0.707
rhs
Putative RHS protein; Similar to Photorhabdus luminescens Rhs Rhs-corE SWALL:AAN64198 (EMBL:AY144117) (1469 aa) fasta scores: E(): 3.1e-128, 41.64% id in 1395 aa, and to Ralstonia solanacearum putative RHS-related transmembrane protein rsp1137 or rs05482 SWALL:Q8XQT2 (EMBL:AL646083) (1517 aa) fasta scores: E(): 3e-74, 32.03% id in 1330 aa.
    
   0.688
ECA4278
Rhs-family protein; Similar to Photorhabdus luminescens Rhs Rhs-corE SWALL:AAN64198 (EMBL:AY144117) (1469 aa) fasta scores: E(): 3.6e-127, 42.61% id in 1361 aa, and to Escherichia coli O157:H7 rhs core protein with extension ecs0605 SWALL:Q8X2J4 (EMBL:AP002552) (1616 aa) fasta scores: E(): 3.9e-80, 37.61% id in 1361 aa.
    
   0.688
katB
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
   
 
 0.597
tldD-2
Putative suppressor of the inhibitory activity of the carbon storage regulator CsrA; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri TldD protein or b3244 or c3999 or sf3283 SWALL:TLDD_ECOLI (SWALL:P46473) (481 aa) fasta scores: E(): 6e-95, 54.66% id in 472 aa. Also similar to ECA0273 (55.297% id. in 472 aa overlap).
       0.581
grxA
Glutaredoxin 1; Similar to Escherichia coli, and Shigella flexneri glutaredoxin 1 GrxA or Grx or b0849 or sf0802 SWALL:GLR1_ECOLI (SWALL:P00277) (85 aa) fasta scores: E(): 6e-21, 69.88% id in 83 aa.
  
  
 0.572
fur
Ferric uptake regulation protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ferric uptake regulation protein Fur or b0683 or c0770 or z0831 or ecs0714 SWALL:FUR_ECOLI (SWALL:P06975) (148 aa) fasta scores: E(): 9.2e-52, 91.09% id in 146 aa; Belongs to the Fur family.
  
 
 0.561
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.551
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.537
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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