Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA1271Similar to Neisseria meningitidis biopolymer transport ExbB protein WALL:EXBB_NEIMC (SWALL:P95375) (220 aa) fasta scores: E(): 1e-23, 38.42% id in 216 aa, and to Xanthomonas campestris biopolymer transport ExbB protein or xcc0009 SWALL:EXBB_XANCP (SWALL:O34260) (253 aa) fasta scores: E(): 1.8e-24, 39.81% id in 216 aa. (258 aa)    
Predicted Functional Partners:
ECA1270
Putative biopolymer transport protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri biopolymer transport ExbD protein ExbD or b3005 or c3740 or z4358 or ecs3889 or sf3050 SWALL:EXBD_ECOLI (SWALL:P18784) (141 aa) fasta scores: E(): 1.3e-08, 34.32% id in 134 aa, and to Neisseria gonorrhoeae biopolymer transport ExbD protein ExbD SWALL:EXBD_NEIGO (SWALL:O06434) (144 aa) fasta scores: E(): 1.6e-12, 39% id in 141 aa.
 
 
 0.978
ECA4298
Similar to Neisseria meningitidis biopolymer transport ExbD protein ExbD or nma1983 or nmb1728 SWALL:EXBD_NEIMA (SWALL:P95376) (144 aa) fasta scores: E(): 3.9e-13, 38.57% id in 140 aa, and to Pseudomonas aeruginosa ExbD or ExbD1 or pa0199 SWALL:Q9RMT1 (EMBL:AF190125) (133 aa) fasta scores: E(): 1.8e-24, 55.63% id in 133 aa.
 
 
 0.911
ECA1272
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.869
tolR
tolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.851
exbD
Biopolymer transport protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri biopolymer transport ExbD protein SWALL:EXBD_ECOLI (SWALL:P18784) (141 aa) fasta scores: E(): 2.1e-36, 68.79% id in 141 aa.
 
 
 0.849
pal
Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.722
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.713
tonB-2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.704
ECA0929
Biopolymer transport protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri biopolymer transport ExbD protein or b3005 or c3740 or z4358 or ecs3889 or sf3050 SWALL:EXBD_ECOLI (SWALL:P18784) (141 aa) fasta scores: E(): 6.4e-07, 29.85% id in 134 aa, and to Anabaena sp. hypothetical protein All5046 all5046 SWALL:Q8YM90 (EMBL:AP003598) (134 aa) fasta scores: E(): 1.2e-08, 33.58% id in 134 aa.
  
 
 0.665
lolC
Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 lipoprotein releasing system transmembrane protein LolC or b1116 or c1391 or z1757 or ecs1494 SWALL:LOLC_ECOLI (SWALL:P75956) (399 aa) fasta scores: E(): 1.7e-115, 79.75% id in 400 aa.
 
     0.541
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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