STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.985
argD
Acetylornithine/succinyldiaminopimelate aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.977
ECA1292
Conserved hypothetical protein; Similar to Escherichia coli protein yffb or b2471 SWALL:YFFB_ECOLI (SWALL:P24178) (118 aa) fasta scores: E(): 8e-24, 61.15% id in 121 aa, and to Yersinia pestis hypothetical protein ypo3052 or y1428 SWALL:Q8ZCD9 (EMBL:AJ414155) (132 aa) fasta scores: E(): 1.1e-27, 67.5% id in 120 aa; Belongs to the ArsC family.
  
    0.837
ECA1290
Similar to Yersinia pestis putative carboxypeptidase ypo3054 or y1426 SWALL:Q8ZCD7 (EMBL:AJ414155) (225 aa) fasta scores: E(): 1.8e-65, 68.34% id in 218 aa, and to Pasteurella multocida hypothetical protein Pm1021 SWALL:Q9CM23 (EMBL:AE006143) (228 aa) fasta scores: E(): 8.7e-46, 51.13% id in 221 aa.
     
 0.815
ECA1289
Similar to Yersinia pestis putative membrane protein ypo3055 SWALL:Q8ZCD6 (EMBL:AJ414155) (64 aa) fasta scores: E(): 1.4e-19, 73.84% id in 65 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm2484 or sty2722 SWALL:Q8XF02 (EMBL:AE008812) (66 aa) fasta scores: E(): 5.5e-17, 66.12% id in 62 aa.
     
 0.803
argG
Argininosuccinate synthase; Similar to Escherichia coli, and Escherichia coli O6 argininosuccinate synthase ArgG or b3172 or c3929 SWALL:ASSY_ECOLI (SWALL:P22767) (446 aa) fasta scores: E(): 1.2e-162, 91.89% id in 444 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
 0.781
argE
Similar to Escherichia coli acetylornithine deacetylase ArgE or b3957 SWALL:ARGE_ECOLI (SWALL:P23908) (383 aa) fasta scores: E(): 2.1e-137, 83.02% id in 383 aa; Belongs to the peptidase M20A family. ArgE subfamily.
  
  
0.721
ECA3115
Similar to Yersinia pestis putative aminotransferase ypo2975 or y1507 SWALL:AAM85078 (EMBL:AJ414154) (411 aa) fasta scores: E(): 4.2e-150, 92.57% id in 404 aa, and to Escherichia coli hypothetical aminotransferase yfdz or b2379 SWALL:YFDZ_ECOLI (SWALL:P77434) (412 aa) fasta scores: E(): 7.1e-147, 90.32% id in 403 aa.
 
  
 0.716
dapD
Similar to Escherichia coli, and Shigella flexneri 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD or b0166 or sf0156 SWALL:DAPD_ECOLI (SWALL:P03948) (274 aa) fasta scores: E(): 4.7e-99, 91.94% id in 273 aa, and to Salmonella typhimurium 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase DapD or stm0213 SWALL:Q8ZRP4 (EMBL:AE008704) (274 aa) fasta scores: E(): 2e-98, 90.11% id in 273 aa; Belongs to the transferase hexapeptide repeat family.
 
   
 0.690
argI
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.685
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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