STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1292Conserved hypothetical protein; Similar to Escherichia coli protein yffb or b2471 SWALL:YFFB_ECOLI (SWALL:P24178) (118 aa) fasta scores: E(): 8e-24, 61.15% id in 121 aa, and to Yersinia pestis hypothetical protein ypo3052 or y1428 SWALL:Q8ZCD9 (EMBL:AJ414155) (132 aa) fasta scores: E(): 1.1e-27, 67.5% id in 120 aa; Belongs to the ArsC family. (125 aa)    
Predicted Functional Partners:
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.829
ECA1290
Similar to Yersinia pestis putative carboxypeptidase ypo3054 or y1426 SWALL:Q8ZCD7 (EMBL:AJ414155) (225 aa) fasta scores: E(): 1.8e-65, 68.34% id in 218 aa, and to Pasteurella multocida hypothetical protein Pm1021 SWALL:Q9CM23 (EMBL:AE006143) (228 aa) fasta scores: E(): 8.7e-46, 51.13% id in 221 aa.
       0.801
ECA1289
Similar to Yersinia pestis putative membrane protein ypo3055 SWALL:Q8ZCD6 (EMBL:AJ414155) (64 aa) fasta scores: E(): 1.4e-19, 73.84% id in 65 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm2484 or sty2722 SWALL:Q8XF02 (EMBL:AE008812) (66 aa) fasta scores: E(): 5.5e-17, 66.12% id in 62 aa.
     
 0.799
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.483
hslO
Heat shock protein (33 kDa chaperonin); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
 
   
 0.476
ECA2365
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein ycgn or b1181 or sf1170 SWALL:AAN42786 (EMBL:AE000216) (153 aa) fasta scores: E(): 6.8e-54, 79.73% id in 148 aa, and to Yersinia pestis hypothetical protein ypo2083 or y2228 SWALL:AAM85788 (EMBL:AJ414151) (148 aa) fasta scores: E(): 7.8e-54, 80.4% id in 148 aa; Belongs to the UPF0260 family.
  
     0.451
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.435
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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