STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cspECold shock-like protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri cold shock-like protein CspE or MsmC or GicA or b0623 or c0714 or z0769 or ecs0662 or sf0657 SWALL:CSPE_ECOLI (SWALL:P36997) (68 aa) fasta scores: E(): 1.4e-23, 92.64% id in 68 aa. (69 aa)    
Predicted Functional Partners:
tufA
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.597
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.516
hisB
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase] HisB or b2022 SWALL:HIS7_ECOLI (SWALL:P06987) (355 aa) fasta scores: E(): 1.6e-119, 82.81% id in 355 aa.
     
 0.514
prfH
Similar to Escherichia coli peptide chain release factor homolog PrfH or b0236 SWALL:RFH_ECOLI (SWALL:P28369) (141 aa) fasta scores: E(): 2.8e-36, 66.66% id in 132 aa.
   
 
 0.509
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
      
 0.507
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
      
 0.507
ECA1293
Similar to Yersinia pestis putative aspartate/glutamate racemase ypo2758 SWALL:Q8ZD34 (EMBL:AJ414153) (231 aa) fasta scores: E(): 2.5e-58, 67.54% id in 228 aa, and to Salmonella typhi hypothetical protein Sty3159 SWALL:Q8Z402 (EMBL:AL627277) (235 aa) fasta scores: E(): 1.6e-49, 55.89% id in 229 aa.
       0.485
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
     
 0.485
rnb
Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
      
 0.477
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.472
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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