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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (227 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.999
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.972
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.944
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or b1288 or z2512 or ecs1861 or sf1293 SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 1.6e-84, 86.97% id in 261 aa.
     
  0.944
fabB
Similar to Escherichia coli, and Escherichia coli O6 3-oxoacyl-[acyl-carrier-protein] synthase I FabB or FabC or b2323 or c2869 SWALL:FABB_ECOLI (SWALL:P14926) (406 aa) fasta scores: E(): 1.3e-137, 92.32% id in 404 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.944
ECA4491
Putative beta-ketoacyl-ACP synthase; Similar to Actinobacillus actinomycetemcomitans beta-ketoacyl-ACP synthase IV FabF SWALL:P70719 (EMBL:D88189) (414 aa) fasta scores: E(): 5.7e-93, 56.52% id in 414 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 3-oxoacyl-[acyl-carrier-protein] synthase II fabf or fabj or b1095 or c1365 or z1734 or ecs1473 or sf1099 SWALL:AAN42718 (EMBL:Z34979) (413 aa) fasta scores: E(): 8.9e-46, 38.74% id in 413 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.943
ECA4494
Putative beta-ketoacyl synthase; Similar to Escherichia coli O157:H7 putative 3-oxoacyl-[ACP] synthase z4863 or ecs4338 SWALL:Q8X6K9 (EMBL:AE005571) (389 aa) fasta scores: E(): 2e-98, 69.58% id in 388 aa, and to Vibrio vulnificus 3-oxoacyl-(acyl-carrier-protein) synthase vv10058 SWALL:AAO08600 (EMBL:AE016797) (395 aa) fasta scores: E(): 1.3e-65, 49.48% id in 390 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.943
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
 0.928
ECA2928
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.902
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.853
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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