STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybeYConserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (159 aa)    
Predicted Functional Partners:
ECA1318
PhoH-like ATP-binding protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PhoH-like protein ybez or b0660 or c0745 or z0809 or ecs0698 or sf0622 SWALL:PHOL_ECOLI (SWALL:P77349) (359 aa) fasta scores: E(): 3.2e-109, 88.92% id in 343 aa, and to Yersinia pestis hypothetical protein ypo2619 or y1194 SWALL:AAM84771 (EMBL:AJ414153) (370 aa) fasta scores: E(): 8.5e-110, 88.33% id in 343 aa.
 
  
 0.952
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.840
corC
Similar to Salmonella typhimurium, and Salmonella typhi magnesium and cobalt efflux protein CorC or stm0667 or sty0712 SWALL:CORC_SALTY (SWALL:Q9R874) (292 aa) fasta scores: E(): 1.5e-92, 85.95% id in 292 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri magnesium and cobalt efflux protein CorC or b0658 or c0743 or z0807 or ecs0696 or sf0624 SWALL:CORC_ECOLI (SWALL:P77392) (292 aa) fasta scores: E(): 2.6e-92, 85.61% id in 292 aa.
  
  
 0.837
era
GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.796
sodA
Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.778
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 0.774
phoH
Phosphate starvation-inducible protein; Similar to Escherichia coli, and Escherichia coli O157:H7 phoh protein PhoH or PsiH or b1020 or z1522 or ecs1266 SWALL:PHOH_ECOLI (SWALL:P31544) (354 aa) fasta scores: E(): 1.1e-85, 86.97% id in 261 aa.
 
  
 0.768
rplQ
50S ribosomal protein L17; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 50S ribosomal protein L17 RplQ or b3294 or c4055 or z4664 or ecs4159 or sf3326 SWALL:RL17_ECOLI (SWALL:P02416) (127 aa) fasta scores: E(): 1.2e-44, 99.16% id in 119 aa.
 
 
 
 0.752
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.747
dgkA
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
  
  
 0.740
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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