STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagAN-acetylglucosamine-6-phosphate deacetylase; Similar to Escherichia coli, and Escherichia coli O157:H7 N-acetylglucosamine-6-phosphate deacetylase NagA or b0677 or z0824 or ecs0707 SWALL:NAGA_ECOLI (SWALL:P15300) (382 aa) fasta scores: E(): 1.7e-109, 72.55% id in 379 aa. (382 aa)    
Predicted Functional Partners:
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 0.999
murQ
Putative phophosugar-binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
  
 0.995
nagE
Similar to Escherichia coli PTS system, N-acetylglucosamine-specific IIABC component NagE or pPstN or b0679 SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 7.8e-62, 45.16% id in 496 aa.
 
  
 0.984
nagK
Conserved hypothetical protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
 
 
 0.979
mrsA
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
     
 0.974
ECA3753
Similar to Vibrio cholerae hypothetical protein Vc0614 SWALL:Q9KUA9 (EMBL:AE004147) (325 aa) fasta scores: E(): 2.6e-27, 40.66% id in 300 aa, and to Vibrio vulnificus predicted N-acetylglucosamine kinase vv11667 SWALL:AAO10084 (EMBL:AE016802) (296 aa) fasta scores: E(): 7.6e-29, 40.66% id in 300 aa.
 
 
 0.969
crr
PTS system, glucose-specific IIa component; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri PTS system, glucose-specific IIA component Crr or Gsr or Iex or Tgs or Tred or b2417 or c2952 or sf2472 SWALL:PTGA_ECOLI (SWALL:P08837) (168 aa) fasta scores: E(): 5e-53, 95.23% id in 168 aa.
 
  
 0.960
ECA3752
Hypothetical protein; Similar to the C-terminal regions of several including Vibrio cholerae hypothetical protein Vc0614 vc0614 SWALL:Q9KUA9 (EMBL:AE004147) (325 aa) fasta scores: E(): 8.8e-12, 31.97% id in 147 aa, and to Vibrio vulnificus predicted N-acetylglucosamine kinase vv11667 SWALL:AAO10084 (EMBL:AE016802) (296 aa) fasta scores: E(): 9.7e-09, 27.66% id in 141 aa.
 
 
 0.960
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.960
manX
PTS system, mannose-specific IIab component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, mannose-specific iiab component ManX or PtsL or GptB or b1817 or c2223 or z2860 or ecs2527 or sf1411 SWALL:PTNA_ECOLI (SWALL:P08186) (322 aa) fasta scores: E(): 5.5e-80, 74.84% id in 322 aa.
    
 0.915
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.