STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagESimilar to Escherichia coli PTS system, N-acetylglucosamine-specific IIABC component NagE or pPstN or b0679 SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 7.8e-62, 45.16% id in 496 aa. (498 aa)    
Predicted Functional Partners:
crr
PTS system, glucose-specific IIa component; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri PTS system, glucose-specific IIA component Crr or Gsr or Iex or Tgs or Tred or b2417 or c2952 or sf2472 SWALL:PTGA_ECOLI (SWALL:P08837) (168 aa) fasta scores: E(): 5e-53, 95.23% id in 168 aa.
 
 0.993
ECA4388
Similar to Erwinia chrysanthemi PTS system, beta-glucoside-specific IIabc component ArbF SWALL:PTBA_ERWCH (SWALL:P26207) (631 aa) fasta scores: E(): 6.6e-81, 37.57% id in 636 aa, and to Escherichia coli PTS system, beta-glucoside-specific IIabc component BglF or BglC or BglS or b3722 SWALL:PTBA_ECOLI (SWALL:P08722) (625 aa) fasta scores: E(): 9.4e-80, 38.6% id in 632 aa.
 
 0.982
nagK
Conserved hypothetical protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
  
 0.981
ECA0860
Similar to Bacillus subtilis PTS system, beta-glucoside-specific IIabc component BglP or N17C SWALL:PTBA_BACSU (SWALL:P40739) (609 aa) fasta scores: E(): 1.1e-61, 39.06% id in 640 aa, and to Escherichia coli PTS system, arbutin-, cellobiose-, and salicin-specific IIabc component ascf or b2715 SWALL:PTDA_ECOLI (SWALL:P24241) (485 aa) fasta scores: E(): 6.6e-58, 38.55% id in 472 aa.
 
 0.978
ECA0661
Similar to Erwinia chrysanthemi PTS system, beta-glucoside-specific IIabc component ArbF SWALL:PTBA_ERWCH (SWALL:P26207) (631 aa) fasta scores: E(): 2.4e-60, 42.76% id in 622 aa, and to Escherichia coli PTS system, beta-glucoside-specific IIabc component BglF or BglC or BglS or b3722 SWALL:PTBA_ECOLI (SWALL:P08722) (625 aa) fasta scores: E(): 6.6e-60, 42.09% id in 639 aa.
 
 0.977
arbF
Similar to Erwinia chrysanthemi pts system, beta-glucoside-specific IIABC component ArbF SWALL:PTBA_ERWCH (SWALL:P26207) (631 aa) fasta scores: E(): 4.9e-165, 70.14% id in 633 aa, and to Escherichia coli PTS system, beta-glucoside-specific IIABC component BglF or BglC or BglS or b3722 SWALL:PTBA_ECOLI (SWALL:P08722) (625 aa) fasta scores: E(): 2e-130, 57.07% id in 629 aa.
 
 0.976
ptsH
PTS system phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri phosphocarrier protein Hpr or b2415 or c2950 or z3681 or ecs3287 or stm2431 or sty2667 or t0426 or sf2470 SWALL:PTHP_ECOLI (SWALL:P07006) (85 aa) fasta scores: E(): 1e-27, 97.64% id in 85 aa.
  
 0.972
nagA
N-acetylglucosamine-6-phosphate deacetylase; Similar to Escherichia coli, and Escherichia coli O157:H7 N-acetylglucosamine-6-phosphate deacetylase NagA or b0677 or z0824 or ecs0707 SWALL:NAGA_ECOLI (SWALL:P15300) (382 aa) fasta scores: E(): 1.7e-109, 72.55% id in 379 aa.
 
  
 0.968
murQ
Putative phophosugar-binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
  
 
 0.949
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.885
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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