STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1333Similar to Yersinia pestis hypothetical protein ypo2637 or y1211 SWALL:AAM84787 (EMBL:AJ414153) (95 aa) fasta scores: E(): 2e-28, 92.39% id in 92 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ybfe or b0685 or z0834 or ecs0716 or sf0608 SWALL:YBFE_ECOLI (SWALL:P75735) (120 aa) fasta scores: E(): 5.4e-25, 81.72% id in 93 aa. (93 aa)    
Predicted Functional Partners:
ilvM
Acetolactate synthase isozyme II small subunit; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri acetolactate synthase isozyme II small subunit IlvM or b3769 or c4691 or sf3844 SWALL:ILVM_ECOLI (SWALL:P13048) (86 aa) fasta scores: E(): 1.8e-18, 63.52% id in 85 aa.
  
     0.769
seqA
Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
    0.695
zapC
Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.679
cpxP
Putative stress resistance protein; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri periplasmic protein cpxp precursor CpxP or b3913/b3914 or c4865 or sf3992 SWALL:CPXP_ECOLI (SWALL:P32158) (166 aa) fasta scores: E(): 6.2e-20, 50% id in 140 aa.
  
     0.665
ECA2748
Similar to Yersinia pestis hypothetical protein Ypo1261 SWALL:Q8ZGM6 (EMBL:AJ414147) (75 aa) fasta scores: E(): 4.5e-22, 85.52% id in 76 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yejl or stm2227 or sty2465 SWALL:Q8XEL6 (EMBL:AE008799) (75 aa) fasta scores: E(): 1.6e-19, 78.94% id in 76 aa; Belongs to the UPF0352 family.
  
    0.630
viaA
Similar to Escherichia coli O6 hypothetical protein YieM SWALL:AAN83105 (EMBL:AE016769) (483 aa) fasta scores: E(): 1.1e-124, 63.03% id in 487 aa.
  
     0.601
ECA4231
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein yife or b3764 or c4686 or z5276 or ecs4699 or sf3840 SWALL:AAN45278 (EMBL:M87049) (112 aa) fasta scores: E(): 2.1e-36, 79.46% id in 112 aa, and to Yersinia pestis hypothetical protein Ypo3903 SWALL:Q8ZAA8 (EMBL:AJ414159) (112 aa) fasta scores: E(): 7.3e-36, 81.25% id in 112 aa.
  
     0.582
crl
Curlin genes transcriptional activator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.
  
     0.540
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
     0.511
ECA2319
Similar to Yersinia pestis hypothetical protein Ypo2187 SWALL:Q8ZEI3 (EMBL:AJ414151) (107 aa) fasta scores: E(): 2e-40, 91.58% id in 107 aa, and to Salmonella typhi hypothetical protein Sty1311 SWALL:Q8Z7E5 (EMBL:AL627269) (109 aa) fasta scores: E(): 1.6e-39, 90.65% id in 107 aa; Belongs to the UPF0263 family.
  
     0.509
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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