STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1348Conserved hypothetical protein; Similar to Salmonella typhi putative pathogenicity island protein sty1731 SWALL:Q8Z6K7 (EMBL:AL627271) (319 aa) fasta scores: E(): 2.5e-75, 58.9% id in 309 aa, and to Salmonella typhimurium orf 319 protein orf319 or stm1389 SWALL:Q9Z4T2 (EMBL:AJ224978) (319 aa) fasta scores: E(): 2.5e-75, 58.9% id in 309 aa. (319 aa)    
Predicted Functional Partners:
phrB
Similar to Escherichia coli deoxyribodipyrimidine photolyase PhrB or Phr or b0708 SWALL:PHR_ECOLI (SWALL:P00914) (472 aa) fasta scores: E(): 5.3e-126, 62.84% id in 471 aa; Belongs to the DNA photolyase family.
  
  
 0.966
ECA1350
Similar to Yersinia pestis hypothetical protein ypo2697 or y1272 SWALL:YQ97_YERPE (SWALL:Q8ZD91) (247 aa) fasta scores: E(): 1.6e-77, 76.92% id in 247 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical protein ybgi or stm0711 or sty0751 SWALL:YBGI_SALTY (SWALL:Q8XFW7) (247 aa) fasta scores: E(): 1.1e-71, 72.06% id in 247 aa.
       0.731
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
     0.531
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
       0.495
ECA1353
Putative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
       0.481
ECA1351
Putative allophanate hydrolase subunit 1; Similar to Salmonella typhimurium putative carboxylase ybgj or stm0712 SWALL:Q8ZQV8 (EMBL:AE008729) (218 aa) fasta scores: E(): 1.1e-61, 72.93% id in 218 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein ybgj or b0711 or z0862 or ecs0736 SWALL:YBGJ_ECOLI (SWALL:P75744) (218 aa) fasta scores: E(): 2.3e-60, 71.56% id in 218 aa.
       0.478
ECA1352
Putative allophanate hydrolase subunit 2; Similar to Yersinia pestis hypothetical protein ypo2699 ypo2699 or y1275 SWALL:AAM84849 (EMBL:AJ414153) (316 aa) fasta scores: E(): 3.6e-83, 69.13% id in 311 aa, and to Escherichia coli hypothetical protein ybgk ybgk or b0712 SWALL:YBGK_ECOLI (SWALL:P75745) (310 aa) fasta scores: E(): 2.6e-79, 64.21% id in 313 aa.
       0.451
nei
Endonuclease VIII; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.432
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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