STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ECA1352Putative allophanate hydrolase subunit 2; Similar to Yersinia pestis hypothetical protein ypo2699 ypo2699 or y1275 SWALL:AAM84849 (EMBL:AJ414153) (316 aa) fasta scores: E(): 3.6e-83, 69.13% id in 311 aa, and to Escherichia coli hypothetical protein ybgk ybgk or b0712 SWALL:YBGK_ECOLI (SWALL:P75745) (310 aa) fasta scores: E(): 2.6e-79, 64.21% id in 313 aa. (314 aa)    
Predicted Functional Partners:
ECA1351
Putative allophanate hydrolase subunit 1; Similar to Salmonella typhimurium putative carboxylase ybgj or stm0712 SWALL:Q8ZQV8 (EMBL:AE008729) (218 aa) fasta scores: E(): 1.1e-61, 72.93% id in 218 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein ybgj or b0711 or z0862 or ecs0736 SWALL:YBGJ_ECOLI (SWALL:P75744) (218 aa) fasta scores: E(): 2.3e-60, 71.56% id in 218 aa.
 0.999
ECA1353
Putative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
 0.991
ECA4488
Putative allophanate hydrolase subunit 1; Similar to Agrobacterium tumefaciens hypothetical protein atu4275 or agr_l_1175 SWALL:Q8U824 (EMBL:AE009356) (235 aa) fasta scores: E(): 2.3e-49, 57.45% id in 228 aa, and to Bradyrhizobium japonicum Blr3632 protein blr3632 SWALL:BAC48897 (EMBL:AP005948) (239 aa) fasta scores: E(): 4.8e-39, 51.64% id in 213 aa.
 0.987
ECA2142
Urea amidolyase; Similar to the C-terminal region of Saccharomyces cerevisiae urea amidolyase [includes: urea carboxylase and allophanate hydrolase] Dur1,2 or ybr208c or ybr1448 SWALL:DUR1_YEAST (SWALL:P32528) (1835 aa) fasta scores: E(): 0, 52.92% id in 1213 aa, and to Pseudomonas fluorescens urea amidolyase homologue uahA SWALL:Q9XAV3 (EMBL:AJ243652) (1213 aa) fasta scores: E(): 0, 51.47% id in 1224 aa.
  
 0.966
pxpA
Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
 0.956
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
   
 
  0.940
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
     
  0.886
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
  
    0.776
nei
Endonuclease VIII; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
    
 0.734
accC
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
  0.650
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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