STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolRtolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (141 aa)    
Predicted Functional Partners:
tolQ
TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.988
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 0.973
ECA4299
Similar to Neisseria meningitidis biopolymer transport ExbB protein ExbB or nma1984 or nmb1729 SWALL:EXBB_NEIMA (SWALL:P57027) (220 aa) fasta scores: E(): 4.3e-20, 40.3% id in 196 aa, and to Pseudomonas aeruginosa ExbB or ExbB1 or pa0198 SWALL:Q9RMT2 (EMBL:AF190125) (239 aa) fasta scores: E(): 2.1e-44, 58.57% id in 239 aa.
 
 
 0.876
pal
Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.871
exbB
Biopolymer transport protein; Similar to Escherichia coli, and Escherichia coli O157:H7 biopolymer transport ExbB protein ExbB or b3006 or z4359 or ecs3890 SWALL:EXBB_ECOLI (SWALL:P18783) (244 aa) fasta scores: E(): 9.3e-57, 75.2% id in 242 aa.
 
 
 0.860
ECA1369
Putative thioesterase; Similar to Yersinia pestis hypothetical protein ypo1120 or y3059 SWALL:Q8ZGZ5 (EMBL:AJ414146) (133 aa) fasta scores: E(): 5e-46, 87.21% id in 133 aa, and to Erwinia chrysanthemi YbgC protein SWALL:Q937K7 (EMBL:AJ297885) (134 aa) fasta scores: E(): 7.4e-45, 82.83% id in 134 aa.
  
  
 0.849
ECA1271
Similar to Neisseria meningitidis biopolymer transport ExbB protein WALL:EXBB_NEIMC (SWALL:P95375) (220 aa) fasta scores: E(): 1e-23, 38.42% id in 216 aa, and to Xanthomonas campestris biopolymer transport ExbB protein or xcc0009 SWALL:EXBB_XANCP (SWALL:O34260) (253 aa) fasta scores: E(): 1.8e-24, 39.81% id in 216 aa.
 
 
 0.815
cpoB
Putative exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
  
 0.744
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
     0.714
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.708
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.