STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpoBPutative exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (258 aa)    
Predicted Functional Partners:
pal
Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.990
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.982
tolR
tolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
  
 0.832
tolQ
TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
  
 0.827
amiB
Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa.
 
  
 0.740
ECA0428
Putative porin; Similar to Porphyromonas gingivalis immunogenic 23 kDa lipoprotein pg3 SWALL:Q9XCA4 (EMBL:AF145799) (223 aa) fasta scores: E(): 2.3e-10, 32.2% id in 236 aa, and to Escherichia coli hypothetical lipoprotein YiaD precursor SWALL:YIAD_ECOLI (SWALL:P37665) (219 aa) fasta scores: E(): 1.5e-09, 35.13% id in 222 aa.
  
  
 0.673
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
 
  
 0.641
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
 
 0.623
tolA
TolA protein; Similar to Erwinia chrysanthemi TolA protein TolA SWALL:Q937K4 (EMBL:AJ297885) (395 aa) fasta scores: E(): 7.1e-61, 79.44% id in 394 aa, and to Escherichia coli tola protein TolA or Cim or ExcC or Lky or b0739 SWALL:TOLA_ECOLI (SWALL:P19934) (421 aa) fasta scores: E(): 6.5e-29, 58.72% id in 424 aa.
 
   0.616
ompH
Outer membrane protein; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
  
  
 0.606
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.