STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
zitBZinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (320 aa)    
Predicted Functional Partners:
copA
Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa.
  
  
 0.743
zntA
Heavy metal-transporting ATPase; Similar to Escherichia coli lead, cadmium, zinc and mercury transporting ATPase ZntA or b3469 SWALL:ATZN_ECOLI (SWALL:P37617) (732 aa) fasta scores: E(): 1.4e-152, 62.53% id in 710 aa, and to Proteus mirabilis putative P-type cation-translocating membrane ATPase PpaA SWALL:O33448 (EMBL:AJ001437) (692 aa) fasta scores: E(): 5.2e-155, 65.26% id in 688 aa.
  
  
 0.563
mntH
Manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
   
 
 0.488
metJ
Repressor of the methionine regulon; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
      
 0.462
zntB
Zinc transport protein; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
 
   
 0.444
cusA
Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.438
cepA
Cation efflux pump; Cation-efflux transporter that may have a role in detoxification.
  
 
 0.415
xylB
Xylulose kinase; Similar to Escherichia coli xylulose kinase XylB SWALL:XYLB_ECOLI (SWALL:P09099) (484 aa) fasta scores: E(): 7.7e-141, 73.81% id in 485 aa.
   
    0.414
rhaB
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.
   
    0.414
aroG
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
       0.408
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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