| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroG | zitB | ECA1381 | ECA1380 | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.408 |
| cepA | copA | ECA4308 | ECA1193 | Cation efflux pump; Cation-efflux transporter that may have a role in detoxification. | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | 0.739 |
| cepA | zitB | ECA4308 | ECA1380 | Cation efflux pump; Cation-efflux transporter that may have a role in detoxification. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.415 |
| cepA | zntA | ECA4308 | ECA4352 | Cation efflux pump; Cation-efflux transporter that may have a role in detoxification. | Heavy metal-transporting ATPase; Similar to Escherichia coli lead, cadmium, zinc and mercury transporting ATPase ZntA or b3469 SWALL:ATZN_ECOLI (SWALL:P37617) (732 aa) fasta scores: E(): 1.4e-152, 62.53% id in 710 aa, and to Proteus mirabilis putative P-type cation-translocating membrane ATPase PpaA SWALL:O33448 (EMBL:AJ001437) (692 aa) fasta scores: E(): 5.2e-155, 65.26% id in 688 aa. | 0.629 |
| cepA | zntB | ECA4308 | ECA1993 | Cation efflux pump; Cation-efflux transporter that may have a role in detoxification. | Zinc transport protein; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. | 0.582 |
| copA | cepA | ECA1193 | ECA4308 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Cation efflux pump; Cation-efflux transporter that may have a role in detoxification. | 0.739 |
| copA | cusA | ECA1193 | ECA1383 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.515 |
| copA | mntH | ECA1193 | ECA0843 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family. | 0.617 |
| copA | zitB | ECA1193 | ECA1380 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.743 |
| copA | zntA | ECA1193 | ECA4352 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Heavy metal-transporting ATPase; Similar to Escherichia coli lead, cadmium, zinc and mercury transporting ATPase ZntA or b3469 SWALL:ATZN_ECOLI (SWALL:P37617) (732 aa) fasta scores: E(): 1.4e-152, 62.53% id in 710 aa, and to Proteus mirabilis putative P-type cation-translocating membrane ATPase PpaA SWALL:O33448 (EMBL:AJ001437) (692 aa) fasta scores: E(): 5.2e-155, 65.26% id in 688 aa. | 0.900 |
| copA | zntB | ECA1193 | ECA1993 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Zinc transport protein; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. | 0.481 |
| cusA | copA | ECA1383 | ECA1193 | Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | 0.515 |
| cusA | zitB | ECA1383 | ECA1380 | Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.438 |
| metJ | zitB | ECA4253 | ECA1380 | Repressor of the methionine regulon; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.462 |
| mntH | copA | ECA0843 | ECA1193 | Manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family. | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | 0.617 |
| mntH | zitB | ECA0843 | ECA1380 | Manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.488 |
| rhaB | zitB | ECA0440 | ECA1380 | Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.414 |
| xylB | zitB | ECA0096 | ECA1380 | Xylulose kinase; Similar to Escherichia coli xylulose kinase XylB SWALL:XYLB_ECOLI (SWALL:P09099) (484 aa) fasta scores: E(): 7.7e-141, 73.81% id in 485 aa. | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.414 |
| zitB | aroG | ECA1380 | ECA1381 | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.408 |
| zitB | cepA | ECA1380 | ECA4308 | Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Cation efflux pump; Cation-efflux transporter that may have a role in detoxification. | 0.415 |