STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cusBSimilar to Escherichia coli putative copper efflux system protein CusB precursor CusB or b0574 SWALL:CUSB_ECOLI (SWALL:P77239) (407 aa) fasta scores: E(): 8.2e-44, 37.94% id in 398 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (493 aa)    
Predicted Functional Partners:
cusA
Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.995
ECA1385
Putative exported protein; Similar to Alcaligenes eutrophus nickel and cobalt resistance protein CnrC precursor SWALL:CNRC_ALCEU (SWALL:P37974) (418 aa) fasta scores: E(): 1.4e-05, 23.51% id in 404 aa, and to Pseudomonas putida heavy metal Rnd efflux outer membrane protein, czcc family pp5385 SWALL:AAN70950 (EMBL:AE016794) (417 aa) fasta scores: E(): 1.5e-28, 32.61% id in 417 aa.
 
 0.971
ECA1386
Putative exported protein; Similar to Escherichia coli hypothetical protein CusX precursor CusX or b0573 SWALL:CUSX_ECOLI (SWALL:P77214) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa, and to Shigella flexneri orf, conserved hypothetical protein ylcc or sf0474 SWALL:AAN42127 (EMBL:AE015079) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa.
 
0.898
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.842
mdtB
Similar to Escherichia coli multidrug transporter MdtB SWALL:BAC06608 (EMBL:AB089188) (1040 aa) fasta scores: E(): 0, 78.92% id in 1039 aa, and to Yersinia pestis acrb/acrd/acrf family membrane protein ypo2848 or y1385 SWALL:Q8ZCW0 (EMBL:AJ414154) (1052 aa) fasta scores: E(): 0, 80.73% id in 1038 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 0.811
copA
Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa.
  
 
 0.714
ECA2932
Similar to Ralstonia solanacearum putative drug efflux lipoprotein rsc3208 or rs02424 SWALL:Q8XUI0 (EMBL:AL646074) (486 aa) fasta scores: E(): 4e-119, 69.19% id in 487 aa, and to Xanthomonas campestris outer membrane protein oprn or xcc0419 SWALL:Q8PDC1 (EMBL:AE012139) (490 aa) fasta scores: E(): 9.1e-110, 65.09% id in 487 aa.
 
 0.652
oprJ
Similar to Pseudomonas aeruginosa outer membrane protein OprJ precursor OprJ or pa4597 SWALL:OPRJ_PSEAE (SWALL:Q51397) (479 aa) fasta scores: E(): 1.2e-94, 57.82% id in 460 aa, and to Pseudomonas putida TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 2.4e-70, 45.14% id in 474 aa, and to Pseudomonas aeruginosa outer membrane protein oprm precursor oprm or oprk or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 1.9e-66, 46.78% id in 466 aa.
 
 0.650
ECA0425
Putative outer membrane efflux protein; Similar to Vibrio cholerae hypothetical protein Vc1606 SWALL:Q9KRN0 (EMBL:AE004238) (476 aa) fasta scores: E(): 6e-69, 44.34% id in 451 aa, and to Shewanella oneidensis outer membrane efflux protein so4090 SWALL:AAN57064 (EMBL:AE015839) (473 aa) fasta scores: E(): 1.2e-68, 45.11% id in 450 aa.
 
 0.645
hasF
Similar to Pseudomonas fluorescens outer membrane protein HasF SWALL:Q9RHT0 (EMBL:AB023289) (442 aa) fasta scores: E(): 1.5e-85, 54.96% id in 433 aa, and to Erwinia chrysanthemi proteases secretion protein PrtF precursor prtF SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 2.1e-75, 48.82% id in 424 aa. Also similar to ECA2781 (48.956% identity in 431 aa overlap).
 
 0.641
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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