STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1385Putative exported protein; Similar to Alcaligenes eutrophus nickel and cobalt resistance protein CnrC precursor SWALL:CNRC_ALCEU (SWALL:P37974) (418 aa) fasta scores: E(): 1.4e-05, 23.51% id in 404 aa, and to Pseudomonas putida heavy metal Rnd efflux outer membrane protein, czcc family pp5385 SWALL:AAN70950 (EMBL:AE016794) (417 aa) fasta scores: E(): 1.5e-28, 32.61% id in 417 aa. (419 aa)    
Predicted Functional Partners:
cusB
Similar to Escherichia coli putative copper efflux system protein CusB precursor CusB or b0574 SWALL:CUSB_ECOLI (SWALL:P77239) (407 aa) fasta scores: E(): 8.2e-44, 37.94% id in 398 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.968
ECA1386
Putative exported protein; Similar to Escherichia coli hypothetical protein CusX precursor CusX or b0573 SWALL:CUSX_ECOLI (SWALL:P77214) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa, and to Shigella flexneri orf, conserved hypothetical protein ylcc or sf0474 SWALL:AAN42127 (EMBL:AE015079) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa.
 
 
 0.949
cusA
Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.942
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.749
ECA1387
Putative membrane protein; Similar to Ralstonia solanacearum hypothetical transmembrane protein rsp0925 or rs05408 SWALL:Q8XRD3 (EMBL:AL646081) (136 aa) fasta scores: E(): 0.11, 26.57% id in 143 aa.
       0.609
aaeA
Putative HlyD family secretion protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.458
ECA0424
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein vc1607 SWALL:Q9KRM9 (EMBL:AE004238) (324 aa) fasta scores: E(): 1.5e-72, 62.03% id in 324 aa.
  
 
 0.458
ECA1096
Similar to Pseudomonas putida protein secretion ABC efflux system, membrane fusion protein pp0803 SWALL:AAN66428 (EMBL:AE016777) (394 aa) fasta scores: E(): 9.1e-67, 54.23% id in 378 aa, and to Escherichia coli O157:H7 putative membrane spanning export protein z0635 or ecs0544 SWALL:Q8XD11 (EMBL:AE005229) (391 aa) fasta scores: E(): 2.9e-66, 54.3% id in 372 aa.
  
 
 0.458
hasE
HlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap).
  
 
 0.458
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
  
 
 0.458
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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