close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wzbProbable protein-tyrosine-phosphatase; Similar to Salmonella typhimurium low molecular weight protein-tyrosine-phosphatase Wzb or stm2117 SWALL:WZB_SALTY (SWALL:Q9F7B2) (149 aa) fasta scores: E(): 1.5e-34, 65.73% id in 143 aa, and to Erwinia amylovora probable low molecular weight protein-tyrosine-phosphatase AmsI SWALL:AMSI_ERWAM (SWALL:Q46630) (144 aa) fasta scores: E(): 5.8e-37, 69.44% id in 144 aa. (144 aa)    
Predicted Functional Partners:
wza
Putative polysaccharide export protein; Similar to Escherichia coli, and Escherichia coli O157:H7 putative polysaccharide export protein Wza precursor Wza or b2062 or z3227 or ecs2867 SWALL:WZA_ECOLI (SWALL:P76388) (379 aa) fasta scores: E(): 3.3e-105, 68.86% id in 379 aa.
  
 0.972
wzc
Similar to Escherichia coli tyrosine-protein kinase Wzc or b2060 SWALL:WZC_ECOLI (SWALL:P76387) (720 aa) fasta scores: E(): 7.9e-146, 57.67% id in 723 aa, and to Erwinia amylovora putative tyrosine-protein kinase AmsA SWALL:AMSA_ERWAM (SWALL:Q46631) (726 aa) fasta scores: E(): 1e-145, 55.18% id in 723 aa.
 
 
 0.968
rfbP
Similar to Salmonella typhimurium undecaprenyl-phosphate galactosephosphotransferase RfbP or stm2082 SWALL:RFBP_SALTY (SWALL:P26406) (476 aa) fasta scores: E(): 3e-129, 64.65% id in 464 aa, and to Erwinia amylovora UDP-galactose-lipid carrier transferase amsG SWALL:AMSG_ERWAM (SWALL:Q46628) (477 aa) fasta scores: E(): 2.8e-131, 66.3% id in 466 aa.
  
  
 0.705
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 
 0.697
ECA2265
Putative membrane protein; Similar to Pseudomonas resinovorans efflux pump SWALL:BAC41699 (EMBL:AB088420) (319 aa) fasta scores: E(): 4.4e-44, 44.08% id in 313 aa, and to Pseudomonas putida transporter, bile acid/na+ symporter family pp0670 SWALL:AAN66295 (EMBL:AE016776) (317 aa) fasta scores: E(): 6.3e-48, 46.45% id in 310 aa.
  
  
 0.690
ECA0502
Putative capsulatr polysaccharide biosynthesis protein; Similar to Rhizobium leguminosarum exopolysaccharide polymerization protein PssP SWALL:O85453 (EMBL:AF067140) (746 aa) fasta scores: E(): 8.1e-10, 23.42% id in 730 aa, and to Vibrio cholerae exopolysaccharide biosynthesis protein, putative vc0937 SWALL:Q9KTG5 (EMBL:AE004176) (737 aa) fasta scores: E(): 1.4e-44, 28.87% id in 717 aa.
  
 
 0.650
wzxE
Enterobacterial common antigen (ECA) biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
     
 0.604
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
 
 0.603
rfbM
Similar to Escherichia coli mannose-1-phosphate guanylyltransferase ManC or CpsB or RfbM or b2049 SWALL:MANC_ECOLI (SWALL:P24174) (478 aa) fasta scores: E(): 2.1e-114, 60.88% id in 473 aa, and to Shigella flexneri mannose-1-phosphate guanyltransferase CpsB_1 or sf2112 SWALL:AAN43651 (EMBL:AE015227) (478 aa) fasta scores: E(): 5.5e-115, 61.31% id in 473 aa; Belongs to the mannose-6-phosphate isomerase type 2 family.
     
 0.543
hflC
Putative phage-related protein; HflC and HflK could regulate a protease.
  
    0.533
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (20%) [HD]