STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfbISimilar to Yersinia pestis, and Yersinia pseudotuberculosis CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase AscD or RfbI or ypo3116 or y1067 SWALL:ASCD_YERPE (SWALL:P37911) (328 aa) fasta scores: E(): 2.8e-45, 45.7% id in 326 aa, and to Salmonella typhimurium RfbI protein or stm2093 SWALL:RFBI_SALTY (SWALL:P26395) (330 aa) fasta scores: E(): 1.1e-50, 46.01% id in 326 aa. (319 aa)    
Predicted Functional Partners:
rfbG
Similar to Salmonella typhimurium CDP-glucose 4,6-dehydratase RfbG or stm2091 SWALL:RFBG_SALTY (SWALL:P26397) (359 aa) fasta scores: E(): 5e-105, 68.92% id in 354 aa, and to Yersinia pseudotuberculosis cdp-glucose-4,6-dehydratase DdhB SWALL:Q8GJ99 (EMBL:AF461768) (391 aa) fasta scores: E(): 2.4e-111, 71.19% id in 361 aa.
  
 
 0.982
rfbH
CDP-4-keto-6-deoxy-D-glucose-3-dehydratase; Similar to Salmonella typhimurium lipopolysaccharide biosynthesis protein RfbH or stm2090 SWALL:RFBH_SALTY (SWALL:P26398) (437 aa) fasta scores: E(): 3.5e-143, 78.94% id in 437 aa, and to Yersinia pestis CDP-4-keto-6-deoxy-D-glucose-3-dehydratase DdhC or ypo3113 SWALL:Q9RCD0 (EMBL:AJ251713) (437 aa) fasta scores: E(): 2.7e-142, 78.26% id in 437 aa; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.962
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.954
fadF
Similar to Escherichia coli 2,4-dienoyl-CoA reductase [NADPH] FadH or b3081 SWALL:FADH_ECOLI (SWALL:P42593) (671 aa) fasta scores: E(): 1e-145, 69.35% id in 682 aa, and to Pseudomonas putida 2,4-dienoyl-coA reductase FadH SWALL:AAN67622 (EMBL:AE016781) (693 aa) fasta scores: E(): 8.6e-160, 64.12% id in 683 aa.
  
 0.945
aegA
Anaerobically expressed oxidoreductase; Similar to Escherichia coli aega protein AegA or b2468 SWALL:AEGA_ECOLI (SWALL:P37127) (659 aa) fasta scores: E(): 3.7e-149, 61.43% id in 656 aa, and to Salmonella typhimurium putative oxidoreductase aega or stm2479 SWALL:Q8ZN79 (EMBL:AE008811) (653 aa) fasta scores: E(): 6e-147, 60.7% id in 649 aa.
  
 0.937
gltD
Similar to Escherichia coli glutamate synthase [NADPH] small chain GltD or AspB or b3213 SWALL:GLTD_ECOLI (SWALL:P09832) (471 aa) fasta scores: E(): 5e-153, 85.56% id in 471 aa.
  
 0.920
ECA2073
Probable oxidoreductase; Similar to Salvelinus fontinalis NADPH:adrenodoxin oxidoreductase, mitochondrial precursor SWALL:ADRO_SALFO (SWALL:P82861) (498 aa) fasta scores: E(): 1.5e-23, 31.73% id in 460 aa, and to Rhodococcus rhodochrous adrenodoxin reductase-like XplB SWALL:Q8GPH8 (EMBL:AF449421) (425 aa) fasta scores: E(): 2.2e-52, 40.32% id in 429 aa.
  
 0.920
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.919
rfbF
Similar to Yersinia pestis, and Yersinia pseudotuberculosis glucose-1-phosphate cytidylyltransferase DdhA or ypo3115 or y1068 SWALL:AAN23053 (EMBL:AJ414155) (261 aa) fasta scores: E(): 1.9e-88, 80.54% id in 257 aa, and to Salmonella typhimurium glucose-1-phosphate cytidylyltransferase RfbF or stm2092 SWALL:RFBF_SALTY (SWALL:P26396) (257 aa) fasta scores: E(): 4.3e-86, 78.2% id in 257 aa.
  
 
 0.902
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.877
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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