STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpcHSimilar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 4.9e-22, 32.4% id in 250 aa; Belongs to the HpcH/HpaI aldolase family. (260 aa)    
Predicted Functional Partners:
ECA0280
Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or b2661 SWALL:GABD_ECOLI (SWALL:P25526) (482 aa) fasta scores: E(): 8.3e-102, 55.41% id in 480 aa, and to Photorhabdus luminescens Orf17 SWALL:AAO17183 (EMBL:AF346500) (490 aa) fasta scores: E(): 6e-104, 57.74% id in 478 aa.
  
 
 0.905
gabD
Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or b2661 SWALL:GABD_ECOLI (SWALL:P25526) (482 aa) fasta scores: E(): 6e-122, 65.76% id in 482 aa.
  
 
 0.905
ECA1426
Putative thiamine pyrophosphate enzyme; Similar to Bacillus subtilis acetolactate synthase large subunit IlvB SWALL:ILVB_BACSU (SWALL:P37251) (573 aa) fasta scores: E(): 5.9e-45, 32.32% id in 563 aa; Belongs to the TPP enzyme family.
       0.768
ECA1427
Similar to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB1 or la0235 SWALL:AAN47434 (EMBL:AE011212) (321 aa) fasta scores: E(): 0.0023, 23.05% id in 321 aa, and to Pyrococcus horikoshii 306aa long hypothetical UDP-glucose 4-epimerase ph1742 SWALL:O59375 (EMBL:AP000007) (306 aa) fasta scores: E(): 0.011, 28.63% id in 213 aa.
  
    0.767
nahO
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.720
ECA1430
Similar to Cicer arietinum dTDP-glucose 4-6-dehydratase SWALL:Q9SMJ5 (EMBL:AJ275318) (346 aa) fasta scores: E(): 1.7e-10, 28.52% id in 284 aa, and to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB4 or la1661 SWALL:AAN48860 (EMBL:AE011344) (369 aa) fasta scores: E(): 1.2e-09, 28.67% id in 279 aa.
  
    0.679
nahM
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.678
rfbF
Similar to Yersinia pestis, and Yersinia pseudotuberculosis glucose-1-phosphate cytidylyltransferase DdhA or ypo3115 or y1068 SWALL:AAN23053 (EMBL:AJ414155) (261 aa) fasta scores: E(): 1.9e-88, 80.54% id in 257 aa, and to Salmonella typhimurium glucose-1-phosphate cytidylyltransferase RfbF or stm2092 SWALL:RFBF_SALTY (SWALL:P26396) (257 aa) fasta scores: E(): 4.3e-86, 78.2% id in 257 aa.
  
    0.488
rfbH
CDP-4-keto-6-deoxy-D-glucose-3-dehydratase; Similar to Salmonella typhimurium lipopolysaccharide biosynthesis protein RfbH or stm2090 SWALL:RFBH_SALTY (SWALL:P26398) (437 aa) fasta scores: E(): 3.5e-143, 78.94% id in 437 aa, and to Yersinia pestis CDP-4-keto-6-deoxy-D-glucose-3-dehydratase DdhC or ypo3113 SWALL:Q9RCD0 (EMBL:AJ251713) (437 aa) fasta scores: E(): 2.7e-142, 78.26% id in 437 aa; Belongs to the DegT/DnrJ/EryC1 family.
  
    0.468
rfbG
Similar to Salmonella typhimurium CDP-glucose 4,6-dehydratase RfbG or stm2091 SWALL:RFBG_SALTY (SWALL:P26397) (359 aa) fasta scores: E(): 5e-105, 68.92% id in 354 aa, and to Yersinia pseudotuberculosis cdp-glucose-4,6-dehydratase DdhB SWALL:Q8GJ99 (EMBL:AF461768) (391 aa) fasta scores: E(): 2.4e-111, 71.19% id in 361 aa.
  
    0.459
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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