Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hpcHSimilar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 4.9e-22, 32.4% id in 250 aa; Belongs to the HpcH/HpaI aldolase family. (260 aa)    
Predicted Functional Partners:
ECA1426
Putative thiamine pyrophosphate enzyme; Similar to Bacillus subtilis acetolactate synthase large subunit IlvB SWALL:ILVB_BACSU (SWALL:P37251) (573 aa) fasta scores: E(): 5.9e-45, 32.32% id in 563 aa; Belongs to the TPP enzyme family.
       0.766
ECA1427
Similar to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB1 or la0235 SWALL:AAN47434 (EMBL:AE011212) (321 aa) fasta scores: E(): 0.0023, 23.05% id in 321 aa, and to Pyrococcus horikoshii 306aa long hypothetical UDP-glucose 4-epimerase ph1742 SWALL:O59375 (EMBL:AP000007) (306 aa) fasta scores: E(): 0.011, 28.63% id in 213 aa.
  
    0.765
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
 
 0.759
gudD
Glucarate dehydratase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucarate dehydratase GudD or b2787 or z4102 or ecs3647 SWALL:GUDH_ECOLI (SWALL:P76637) (445 aa) fasta scores: E(): 2.3e-156, 84.87% id in 443 aa.
 
 
 0.757
garD
D-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
 
 
 0.740
nahO
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.715
ECA0489
Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 4.9e-13, 26.16% id in 279 aa, and to Pseudomonas aeruginosa probable 3-hydroxyisobutyrate dehydrogenase pa3312 SWALL:Q9HYT2 (EMBL:AE004753) (296 aa) fasta scores: E(): 3.4e-17, 31.09% id in 283 aa.
 
 
 0.682
ECA1430
Similar to Cicer arietinum dTDP-glucose 4-6-dehydratase SWALL:Q9SMJ5 (EMBL:AJ275318) (346 aa) fasta scores: E(): 1.7e-10, 28.52% id in 284 aa, and to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB4 or la1661 SWALL:AAN48860 (EMBL:AE011344) (369 aa) fasta scores: E(): 1.2e-09, 28.67% id in 279 aa.
  
    0.678
LfeW
Similar to Salmonella typhimurium putative mandelate racemase / muconate lactonizing enzyme family stm3697 SWALL:Q8ZL58 (EMBL:AE008872) (398 aa) fasta scores: E(): 9.9e-148, 92.96% id in 398 aa, and to Pseudomonas putida mandelate racemase mdlA SWALL:MANR_PSEPU (SWALL:P11444) (359 aa) fasta scores: E(): 1.3e-22, 28.32% id in 353 aa.
 
 
 0.672
nahM
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.672
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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