STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1430Similar to Cicer arietinum dTDP-glucose 4-6-dehydratase SWALL:Q9SMJ5 (EMBL:AJ275318) (346 aa) fasta scores: E(): 1.7e-10, 28.52% id in 284 aa, and to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB4 or la1661 SWALL:AAN48860 (EMBL:AE011344) (369 aa) fasta scores: E(): 1.2e-09, 28.67% id in 279 aa. (351 aa)    
Predicted Functional Partners:
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.803
rfbF
Similar to Yersinia pestis, and Yersinia pseudotuberculosis glucose-1-phosphate cytidylyltransferase DdhA or ypo3115 or y1068 SWALL:AAN23053 (EMBL:AJ414155) (261 aa) fasta scores: E(): 1.9e-88, 80.54% id in 257 aa, and to Salmonella typhimurium glucose-1-phosphate cytidylyltransferase RfbF or stm2092 SWALL:RFBF_SALTY (SWALL:P26396) (257 aa) fasta scores: E(): 4.3e-86, 78.2% id in 257 aa.
 
 0.788
nahO
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.776
nahM
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.773
rfbH
CDP-4-keto-6-deoxy-D-glucose-3-dehydratase; Similar to Salmonella typhimurium lipopolysaccharide biosynthesis protein RfbH or stm2090 SWALL:RFBH_SALTY (SWALL:P26398) (437 aa) fasta scores: E(): 3.5e-143, 78.94% id in 437 aa, and to Yersinia pestis CDP-4-keto-6-deoxy-D-glucose-3-dehydratase DdhC or ypo3113 SWALL:Q9RCD0 (EMBL:AJ251713) (437 aa) fasta scores: E(): 2.7e-142, 78.26% id in 437 aa; Belongs to the DegT/DnrJ/EryC1 family.
 
 
 0.759
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.757
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.704
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
  0.699
ECA1426
Putative thiamine pyrophosphate enzyme; Similar to Bacillus subtilis acetolactate synthase large subunit IlvB SWALL:ILVB_BACSU (SWALL:P37251) (573 aa) fasta scores: E(): 5.9e-45, 32.32% id in 563 aa; Belongs to the TPP enzyme family.
   
   0.689
ECA1427
Similar to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB1 or la0235 SWALL:AAN47434 (EMBL:AE011212) (321 aa) fasta scores: E(): 0.0023, 23.05% id in 321 aa, and to Pyrococcus horikoshii 306aa long hypothetical UDP-glucose 4-epimerase ph1742 SWALL:O59375 (EMBL:AP000007) (306 aa) fasta scores: E(): 0.011, 28.63% id in 213 aa.
       0.682
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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