Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (283 aa)    
Predicted Functional Partners:
rfbC
dTDP-6-deoxy-D-glucose-3,5 epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
rffG
Similar to Escherichia coli dTDP-glucose 4,6-dehydratase RffG or b3788 SWALL:RFFG_ECOLI (SWALL:P27830) (355 aa) fasta scores: E(): 6.4e-119, 83% id in 353 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
 0.998
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.996
rfbM
Similar to Escherichia coli mannose-1-phosphate guanylyltransferase ManC or CpsB or RfbM or b2049 SWALL:MANC_ECOLI (SWALL:P24174) (478 aa) fasta scores: E(): 2.1e-114, 60.88% id in 473 aa, and to Shigella flexneri mannose-1-phosphate guanyltransferase CpsB_1 or sf2112 SWALL:AAN43651 (EMBL:AE015227) (478 aa) fasta scores: E(): 5.5e-115, 61.31% id in 473 aa; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.870
wcaJ
Putative capsular polysaccharide biosynthesis protein; Similar to Escherichia coli putative colanic biosynthesis UDP-glucose lipid carrier transferase WcaJ or b2047 SWALL:WCAJ_ECOLI (SWALL:P71241) (464 aa) fasta scores: E(): 6.8e-69, 43.62% id in 463 aa, and to Klebsiella pneumoniae probable CPS biosynthesis glycosyltransferase SWALL:YC14_KLEPN (SWALL:Q48460) (465 aa) fasta scores: E(): 1e-69, 43.95% id in 455 aa.
 
  
 0.824
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.823
rfbP
Similar to Salmonella typhimurium undecaprenyl-phosphate galactosephosphotransferase RfbP or stm2082 SWALL:RFBP_SALTY (SWALL:P26406) (476 aa) fasta scores: E(): 3e-129, 64.65% id in 464 aa, and to Erwinia amylovora UDP-galactose-lipid carrier transferase amsG SWALL:AMSG_ERWAM (SWALL:Q46628) (477 aa) fasta scores: E(): 2.8e-131, 66.3% id in 466 aa.
 
  
 0.820
rfbG
Similar to Salmonella typhimurium CDP-glucose 4,6-dehydratase RfbG or stm2091 SWALL:RFBG_SALTY (SWALL:P26397) (359 aa) fasta scores: E(): 5e-105, 68.92% id in 354 aa, and to Yersinia pseudotuberculosis cdp-glucose-4,6-dehydratase DdhB SWALL:Q8GJ99 (EMBL:AF461768) (391 aa) fasta scores: E(): 2.4e-111, 71.19% id in 361 aa.
  
 0.734
rfbF
Similar to Yersinia pestis, and Yersinia pseudotuberculosis glucose-1-phosphate cytidylyltransferase DdhA or ypo3115 or y1068 SWALL:AAN23053 (EMBL:AJ414155) (261 aa) fasta scores: E(): 1.9e-88, 80.54% id in 257 aa, and to Salmonella typhimurium glucose-1-phosphate cytidylyltransferase RfbF or stm2092 SWALL:RFBF_SALTY (SWALL:P26396) (257 aa) fasta scores: E(): 4.3e-86, 78.2% id in 257 aa.
  
 
 0.688
ECA1430
Similar to Cicer arietinum dTDP-glucose 4-6-dehydratase SWALL:Q9SMJ5 (EMBL:AJ275318) (346 aa) fasta scores: E(): 1.7e-10, 28.52% id in 284 aa, and to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB4 or la1661 SWALL:AAN48860 (EMBL:AE011344) (369 aa) fasta scores: E(): 1.2e-09, 28.67% id in 279 aa.
 
 0.642
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.